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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GREM2 All Species: 29.39
Human Site: Y67 Identified Species: 71.85
UniProt: Q9H772 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H772 NP_071914.3 168 19320 Y67 L V V T E R K Y L K S D W C K
Chimpanzee Pan troglodytes XP_523036 240 26508 Y144 L H V T E R K Y L K R D W C K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547488 168 19309 Y67 L V V T E R K Y L K S D W C K
Cat Felis silvestris
Mouse Mus musculus O88273 168 19316 Y67 L V V T E R K Y L K S D W C K
Rat Rattus norvegicus O35793 184 20661 Y88 L H V T E R K Y L K R D W C K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519831 144 16367 P58 R D W C K T Q P L K Q T I R E
Chicken Gallus gallus O73755 184 21148 Y88 L H I T E R K Y L K R D W C K
Frog Xenopus laevis O73754 182 20356 Y86 L H V T E R K Y L K R D W C K
Zebra Danio Brachydanio rerio NP_001017704 166 18864 Y65 L V V T E K K Y L K S D W C K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001023876 339 38075 L169 P V E S R F R L G T A Y Q L E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.5 N.A. 98.2 N.A. 95.2 53.2 N.A. 46.4 55.4 54.4 70.8 N.A. N.A. N.A. 20.3 N.A.
Protein Similarity: 100 53.3 N.A. 99.4 N.A. 97.6 67.9 N.A. 59.5 70.6 70.8 83.3 N.A. N.A. N.A. 30.3 N.A.
P-Site Identity: 100 86.6 N.A. 100 N.A. 100 86.6 N.A. 13.3 80 86.6 93.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 86.6 N.A. 100 N.A. 100 86.6 N.A. 33.3 86.6 86.6 100 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 80 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 80 0 0 0 % D
% Glu: 0 0 10 0 80 0 0 0 0 0 0 0 0 0 20 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 10 10 80 0 0 90 0 0 0 0 80 % K
% Leu: 80 0 0 0 0 0 0 10 90 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 10 0 10 0 0 % Q
% Arg: 10 0 0 0 10 70 10 0 0 0 40 0 0 10 0 % R
% Ser: 0 0 0 10 0 0 0 0 0 0 40 0 0 0 0 % S
% Thr: 0 0 0 80 0 10 0 0 0 10 0 10 0 0 0 % T
% Val: 0 50 70 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 80 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _