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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPF2
All Species:
37.88
Human Site:
S197
Identified Species:
59.52
UniProt:
Q9H7B2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7B2
NP_115570.1
306
35583
S197
N
G
K
I
Y
F
R
S
Y
K
L
L
L
K
K
Chimpanzee
Pan troglodytes
XP_001156382
273
31615
K166
K
I
Y
F
R
S
Y
K
L
L
L
K
K
S
G
Rhesus Macaque
Macaca mulatta
XP_001087115
306
35515
S197
N
G
K
I
Y
F
R
S
Y
K
L
L
L
K
K
Dog
Lupus familis
XP_854452
306
35620
S197
N
G
K
I
Y
F
R
S
Y
K
L
L
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ80
306
35345
S197
N
G
K
V
Y
F
R
S
Y
K
L
L
L
K
K
Rat
Rattus norvegicus
NP_001099861
306
35238
S197
N
G
K
V
Y
F
R
S
Y
K
L
L
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426181
306
35059
S197
D
G
K
I
Y
M
R
S
Y
K
V
L
L
K
K
Frog
Xenopus laevis
NP_001080306
308
35344
S197
D
G
K
I
F
M
R
S
Y
K
V
L
M
K
K
Zebra Danio
Brachydanio rerio
NP_999913
308
35443
S197
E
G
K
I
Y
M
R
S
Y
K
V
L
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEB3
320
36479
R196
D
D
M
N
I
L
M
R
S
Y
R
I
L
L
K
Honey Bee
Apis mellifera
XP_623712
323
37466
S204
E
N
K
I
F
L
R
S
Y
R
I
L
L
K
K
Nematode Worm
Caenorhab. elegans
Q9N3F0
297
33442
L186
T
V
I
V
F
T
A
L
D
E
T
N
L
A
L
Sea Urchin
Strong. purpuratus
XP_001179886
326
37498
S189
D
E
K
I
L
M
R
S
Y
K
V
I
L
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUG5
314
35709
V197
S
A
I
S
P
T
K
V
F
L
T
H
C
A
L
Baker's Yeast
Sacchar. cerevisiae
P36160
344
39580
E194
Q
G
D
F
Q
D
G
E
P
L
P
N
V
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
98.6
95.7
N.A.
92.1
92.4
N.A.
N.A.
85.6
79.2
70.7
N.A.
45.9
47.9
41.1
54.9
Protein Similarity:
100
89.2
99.6
98
N.A.
96.7
97
N.A.
N.A.
93.4
90.9
81.8
N.A.
64
64.4
58.1
71.4
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
80
66.6
80
N.A.
13.3
60
6.6
60
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
86.6
N.A.
26.6
80
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.9
41.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.3
55.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
0
0
0
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
27
7
7
0
0
7
0
0
7
0
0
0
0
0
0
% D
% Glu:
14
7
0
0
0
0
0
7
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
14
20
34
0
0
7
0
0
0
0
0
7
% F
% Gly:
0
60
0
0
0
0
7
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
14
54
7
0
0
0
0
0
7
14
0
0
0
% I
% Lys:
7
0
67
0
0
0
7
7
0
60
0
7
7
67
74
% K
% Leu:
0
0
0
0
7
14
0
7
7
20
40
60
74
14
14
% L
% Met:
0
0
7
0
0
27
7
0
0
0
0
0
7
0
0
% M
% Asn:
34
7
0
7
0
0
0
0
0
0
0
14
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
7
0
7
0
0
0
0
% P
% Gln:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
67
7
0
7
7
0
0
0
0
% R
% Ser:
7
0
0
7
0
7
0
67
7
0
0
0
0
7
0
% S
% Thr:
7
0
0
0
0
14
0
0
0
0
14
0
0
0
0
% T
% Val:
0
7
0
20
0
0
0
7
0
0
27
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
47
0
7
0
67
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _