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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPF2
All Species:
27.27
Human Site:
S274
Identified Species:
42.86
UniProt:
Q9H7B2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7B2
NP_115570.1
306
35583
S274
H
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
M
Chimpanzee
Pan troglodytes
XP_001156382
273
31615
K242
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
M
K
Rhesus Macaque
Macaca mulatta
XP_001087115
306
35515
S274
H
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
M
Dog
Lupus familis
XP_854452
306
35620
S274
H
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ80
306
35345
S274
H
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
M
Rat
Rattus norvegicus
NP_001099861
306
35238
S274
H
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426181
306
35059
S274
H
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
M
Frog
Xenopus laevis
NP_001080306
308
35344
S274
H
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
M
Zebra Danio
Brachydanio rerio
NP_999913
308
35443
N274
H
M
Q
K
Q
D
L
N
K
L
Q
T
R
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEB3
320
36479
G274
H
L
G
K
Q
Q
T
G
S
I
Q
T
R
R
V
Honey Bee
Apis mellifera
XP_623712
323
37466
N281
H
V
G
I
Q
N
I
N
T
I
Q
T
R
K
M
Nematode Worm
Caenorhab. elegans
Q9N3F0
297
33442
V264
F
G
N
Q
L
A
R
V
H
V
G
K
Q
R
T
Sea Urchin
Strong. purpuratus
XP_001179886
326
37498
A266
H
M
E
K
Q
D
L
A
K
L
Q
I
R
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUG5
314
35709
K278
Y
M
P
D
Q
K
L
K
E
M
K
L
F
D
K
Baker's Yeast
Sacchar. cerevisiae
P36160
344
39580
G283
H
M
G
K
Q
D
L
G
K
L
Q
T
R
K
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
98.6
95.7
N.A.
92.1
92.4
N.A.
N.A.
85.6
79.2
70.7
N.A.
45.9
47.9
41.1
54.9
Protein Similarity:
100
89.2
99.6
98
N.A.
96.7
97
N.A.
N.A.
93.4
90.9
81.8
N.A.
64
64.4
58.1
71.4
P-Site Identity:
100
0
100
100
N.A.
100
93.3
N.A.
N.A.
100
100
93.3
N.A.
40
46.6
0
73.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
66.6
80
26.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.9
41.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.3
55.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
86.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
67
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
7
20
0
0
0
0
14
0
0
7
0
0
0
0
% G
% His:
80
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
7
0
0
14
0
7
0
0
0
% I
% Lys:
0
0
7
74
0
7
0
14
67
0
7
7
7
74
14
% K
% Leu:
0
7
0
0
7
7
74
0
7
67
0
7
0
0
0
% L
% Met:
7
74
0
0
0
0
0
0
0
7
0
0
0
7
60
% M
% Asn:
0
0
7
0
0
7
0
14
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
54
14
87
7
0
0
0
7
80
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
7
80
14
0
% R
% Ser:
0
0
0
0
0
0
7
47
7
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
0
7
0
7
74
0
0
7
% T
% Val:
0
7
0
0
0
0
0
7
0
7
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _