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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF2 All Species: 45.76
Human Site: S88 Identified Species: 71.9
UniProt: Q9H7B2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7B2 NP_115570.1 306 35583 S88 F S K K S D C S L F M F G S H
Chimpanzee Pan troglodytes XP_001156382 273 31615 F57 K K S D C S L F M F G S H N K
Rhesus Macaque Macaca mulatta XP_001087115 306 35515 S88 F S K K S D C S L F M F G S H
Dog Lupus familis XP_854452 306 35620 S88 F S K K S D C S L F M F G S H
Cat Felis silvestris
Mouse Mus musculus Q9JJ80 306 35345 S88 F S K K S D C S L F M F G S H
Rat Rattus norvegicus NP_001099861 306 35238 S88 F S K K S D C S L F M F G S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426181 306 35059 S88 F S K K S D C S L F L F G S H
Frog Xenopus laevis NP_001080306 308 35344 S88 F A K K S D C S L F V F G S H
Zebra Danio Brachydanio rerio NP_999913 308 35443 S88 F S K K S D C S L F L F G S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEB3 320 36479 A87 L T M K N D A A L F T F G S T
Honey Bee Apis mellifera XP_623712 323 37466 S95 F C A K Y N A S L F M I A L H
Nematode Worm Caenorhab. elegans Q9N3F0 297 33442 R77 E D E T P I V R A G S K F D T
Sea Urchin Strong. purpuratus XP_001179886 326 37498 S80 M S Q K N D A S L F A F G S H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LUG5 314 35709 S88 F S Q K T D C S I F V Y G S H
Baker's Yeast Sacchar. cerevisiae P36160 344 39580 S85 F S E K N D C S L M V L M T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 98.6 95.7 N.A. 92.1 92.4 N.A. N.A. 85.6 79.2 70.7 N.A. 45.9 47.9 41.1 54.9
Protein Similarity: 100 89.2 99.6 98 N.A. 96.7 97 N.A. N.A. 93.4 90.9 81.8 N.A. 64 64.4 58.1 71.4
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 93.3 86.6 93.3 N.A. 46.6 46.6 0 66.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 66.6 53.3 6.6 80
Percent
Protein Identity: N.A. N.A. N.A. 43.9 41.8 N.A.
Protein Similarity: N.A. N.A. N.A. 63.3 55.2 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 100 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 0 20 7 7 0 7 0 7 0 0 % A
% Cys: 0 7 0 0 7 0 67 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 80 0 0 0 0 0 0 0 7 0 % D
% Glu: 7 0 14 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 74 0 0 0 0 0 0 7 0 87 0 67 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 7 0 74 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 74 % H
% Ile: 0 0 0 0 0 7 0 0 7 0 0 7 0 0 0 % I
% Lys: 7 7 54 87 0 0 0 0 0 0 0 7 0 0 7 % K
% Leu: 7 0 0 0 0 0 7 0 80 0 14 7 0 7 0 % L
% Met: 7 0 7 0 0 0 0 0 7 7 40 0 7 0 0 % M
% Asn: 0 0 0 0 20 7 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % R
% Ser: 0 67 7 0 54 7 0 80 0 0 7 7 0 74 7 % S
% Thr: 0 7 0 7 7 0 0 0 0 0 7 0 0 7 14 % T
% Val: 0 0 0 0 0 0 7 0 0 0 20 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _