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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF2 All Species: 32.12
Human Site: T209 Identified Species: 50.48
UniProt: Q9H7B2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7B2 NP_115570.1 306 35583 T209 L K K S G C R T P R I E L E E
Chimpanzee Pan troglodytes XP_001156382 273 31615 R178 K S G C R T P R I E L E E M G
Rhesus Macaque Macaca mulatta XP_001087115 306 35515 T209 L K K S G C R T P R I E L E E
Dog Lupus familis XP_854452 306 35620 T209 L K K S G C R T P R I E L E E
Cat Felis silvestris
Mouse Mus musculus Q9JJ80 306 35345 T209 L K K S G C R T P R I E L E E
Rat Rattus norvegicus NP_001099861 306 35238 T209 L K K S G C R T P R I E L E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426181 306 35059 I209 L K K S G C K I P R I E L E D
Frog Xenopus laevis NP_001080306 308 35344 T209 M K K S G C R T P R I E L E E
Zebra Danio Brachydanio rerio NP_999913 308 35443 T209 L K K S G C R T P R I E L E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEB3 320 36479 R208 L L K K S G Q R T P R I E L E
Honey Bee Apis mellifera XP_623712 323 37466 V216 L K K S N S R V P R I E L E E
Nematode Worm Caenorhab. elegans Q9N3F0 297 33442 P198 L A L R V Y R P M L K K S A T
Sea Urchin Strong. purpuratus XP_001179886 326 37498 T201 L K K S G S R T P R V E L T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LUG5 314 35709 S209 C A L K L K K S G S I V P R M
Baker's Yeast Sacchar. cerevisiae P36160 344 39580 L206 V L F R V Y K L K S Y K S D Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 98.6 95.7 N.A. 92.1 92.4 N.A. N.A. 85.6 79.2 70.7 N.A. 45.9 47.9 41.1 54.9
Protein Similarity: 100 89.2 99.6 98 N.A. 96.7 97 N.A. N.A. 93.4 90.9 81.8 N.A. 64 64.4 58.1 71.4
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 80 93.3 100 N.A. 20 80 13.3 80
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. 93.3 100 100 N.A. 26.6 80 20 86.6
Percent
Protein Identity: N.A. N.A. N.A. 43.9 41.8 N.A.
Protein Similarity: N.A. N.A. N.A. 63.3 55.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 0 0 0 0 0 0 0 0 7 0 % A
% Cys: 7 0 0 7 0 54 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % D
% Glu: 0 0 0 0 0 0 0 0 0 7 0 74 14 60 67 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 60 7 0 0 7 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 7 0 67 7 0 0 0 % I
% Lys: 7 67 74 14 0 7 20 0 7 0 7 14 0 0 0 % K
% Leu: 74 14 14 0 7 0 0 7 0 7 7 0 67 7 0 % L
% Met: 7 0 0 0 0 0 0 0 7 0 0 0 0 7 7 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 7 7 67 7 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 14 7 0 67 14 0 67 7 0 0 7 0 % R
% Ser: 0 7 0 67 7 14 0 7 0 14 0 0 14 0 0 % S
% Thr: 0 0 0 0 0 7 0 54 7 0 0 0 0 7 7 % T
% Val: 7 0 0 0 14 0 0 7 0 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 14 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _