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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF2 All Species: 46.67
Human Site: T76 Identified Species: 73.33
UniProt: Q9H7B2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7B2 NP_115570.1 306 35583 T76 T R P F E D Q T S L E F F S K
Chimpanzee Pan troglodytes XP_001156382 273 31615 L45 P F E D Q T S L E F F S K K S
Rhesus Macaque Macaca mulatta XP_001087115 306 35515 T76 T R P F E D Q T S L E F F S K
Dog Lupus familis XP_854452 306 35620 T76 T R P F E D Q T S L E F F S K
Cat Felis silvestris
Mouse Mus musculus Q9JJ80 306 35345 T76 T R P F E D Q T S L E F F S K
Rat Rattus norvegicus NP_001099861 306 35238 T76 T R P F E D Q T S L E F F S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426181 306 35059 T76 T R P F E D Q T S L E F F S K
Frog Xenopus laevis NP_001080306 308 35344 T76 T R P F E D Q T S L E F F A K
Zebra Danio Brachydanio rerio NP_999913 308 35443 T76 V R P F E D S T A L E F F S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEB3 320 36479 S75 I T P F D D P S S L E F L T M
Honey Bee Apis mellifera XP_623712 323 37466 T83 I L P F E D I T P V E K F C A
Nematode Worm Caenorhab. elegans Q9N3F0 297 33442 P65 T K M D K H N P Y H L F E D E
Sea Urchin Strong. purpuratus XP_001179886 326 37498 T68 M R P F E D Q T S L E F M S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LUG5 314 35709 T76 P F E S G G E T S L E F F S Q
Baker's Yeast Sacchar. cerevisiae P36160 344 39580 S73 I H P F E D M S P L E F F S E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 98.6 95.7 N.A. 92.1 92.4 N.A. N.A. 85.6 79.2 70.7 N.A. 45.9 47.9 41.1 54.9
Protein Similarity: 100 89.2 99.6 98 N.A. 96.7 97 N.A. N.A. 93.4 90.9 81.8 N.A. 64 64.4 58.1 71.4
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. N.A. 100 93.3 80 N.A. 46.6 46.6 13.3 80
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 100 100 86.6 N.A. 66.6 53.3 33.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 43.9 41.8 N.A.
Protein Similarity: N.A. N.A. N.A. 63.3 55.2 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 14 7 80 0 0 0 0 0 0 0 7 0 % D
% Glu: 0 0 14 0 74 0 7 0 7 0 87 0 7 0 14 % E
% Phe: 0 14 0 80 0 0 0 0 0 7 7 87 74 0 0 % F
% Gly: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % G
% His: 0 7 0 0 0 7 0 0 0 7 0 0 0 0 0 % H
% Ile: 20 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 0 0 7 0 0 0 0 0 0 7 7 7 54 % K
% Leu: 0 7 0 0 0 0 0 7 0 80 7 0 7 0 0 % L
% Met: 7 0 7 0 0 0 7 0 0 0 0 0 7 0 7 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 14 0 80 0 0 0 7 7 14 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 54 0 0 0 0 0 0 0 14 % Q
% Arg: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 0 14 14 67 0 0 7 0 67 7 % S
% Thr: 54 7 0 0 0 7 0 74 0 0 0 0 0 7 0 % T
% Val: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _