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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF2 All Species: 35.76
Human Site: Y53 Identified Species: 56.19
UniProt: Q9H7B2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7B2 NP_115570.1 306 35583 Y53 T K V L K D V Y A L K K P Y G
Chimpanzee Pan troglodytes XP_001156382 273 31615 L22 V L K D V Y A L K K P Y G V L
Rhesus Macaque Macaca mulatta XP_001087115 306 35515 Y53 T Q V L K D V Y A L K K P Y G
Dog Lupus familis XP_854452 306 35620 Y53 T Q V L R D V Y A L K K P Y G
Cat Felis silvestris
Mouse Mus musculus Q9JJ80 306 35345 Y53 T Q V L R D M Y A L K K P Y G
Rat Rattus norvegicus NP_001099861 306 35238 Y53 T Q V L R D V Y A L K K P Y G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426181 306 35059 Y53 T E V L K D I Y A L K K P F A
Frog Xenopus laevis NP_001080306 308 35344 Y53 T Q A L K D I Y A L K K P Y G
Zebra Danio Brachydanio rerio NP_999913 308 35443 Y53 S Q A L K D V Y A L K K P N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEB3 320 36479 Q52 K L C M K D L Q A L K K P L V
Honey Bee Apis mellifera XP_623712 323 37466 Y60 V D F M K D L Y N L K K P D A
Nematode Worm Caenorhab. elegans Q9N3F0 297 33442 I42 G A K T N E I I S H A M M D L
Sea Urchin Strong. purpuratus XP_001179886 326 37498 H45 T A L L T E L H M L R K P H S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LUG5 314 35709 K53 M T E L Y R L K K G G A I R Y
Baker's Yeast Sacchar. cerevisiae P36160 344 39580 S50 H D I M V D L S A L K K P D M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 98.6 95.7 N.A. 92.1 92.4 N.A. N.A. 85.6 79.2 70.7 N.A. 45.9 47.9 41.1 54.9
Protein Similarity: 100 89.2 99.6 98 N.A. 96.7 97 N.A. N.A. 93.4 90.9 81.8 N.A. 64 64.4 58.1 71.4
P-Site Identity: 100 0 93.3 86.6 N.A. 80 86.6 N.A. N.A. 73.3 80 66.6 N.A. 46.6 46.6 0 33.3
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. N.A. 93.3 93.3 80 N.A. 60 60 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. 43.9 41.8 N.A.
Protein Similarity: N.A. N.A. N.A. 63.3 55.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 14 0 0 0 7 0 67 0 7 7 0 0 20 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 7 0 74 0 0 0 0 0 0 0 20 0 % D
% Glu: 0 7 7 0 0 14 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 7 0 0 0 0 0 0 0 0 7 7 0 7 0 40 % G
% His: 7 0 0 0 0 0 0 7 0 7 0 0 0 7 0 % H
% Ile: 0 0 7 0 0 0 20 7 0 0 0 0 7 0 0 % I
% Lys: 7 7 14 0 47 0 0 7 14 7 74 80 0 0 0 % K
% Leu: 0 14 7 67 0 0 34 7 0 80 0 0 0 7 14 % L
% Met: 7 0 0 20 0 0 7 0 7 0 0 7 7 0 7 % M
% Asn: 0 0 0 0 7 0 0 0 7 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 80 0 0 % P
% Gln: 0 40 0 0 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 20 7 0 0 0 0 7 0 0 7 0 % R
% Ser: 7 0 0 0 0 0 0 7 7 0 0 0 0 0 7 % S
% Thr: 54 7 0 7 7 0 0 0 0 0 0 0 0 0 0 % T
% Val: 14 0 40 0 14 0 34 0 0 0 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 7 0 60 0 0 0 7 0 40 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _