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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD3
All Species:
21.82
Human Site:
S118
Identified Species:
40
UniProt:
Q9H7B4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7B4
NP_073580.1
428
49097
S118
K
L
M
D
G
A
P
S
E
S
E
K
L
Y
S
Chimpanzee
Pan troglodytes
XP_514316
454
52196
S118
K
L
M
D
G
A
P
S
E
S
E
K
L
Y
S
Rhesus Macaque
Macaca mulatta
XP_001089022
428
49069
S118
K
L
M
D
G
T
P
S
E
S
E
K
L
Y
S
Dog
Lupus familis
XP_537223
266
30635
W15
V
L
R
K
M
K
M
W
V
I
C
N
A
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWR2
428
49108
S118
K
L
M
D
E
K
P
S
E
S
E
K
L
Y
S
Rat
Rattus norvegicus
Q7M6Z3
433
49630
T123
Q
K
M
H
P
E
R
T
P
S
E
K
L
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513395
408
46852
S104
E
S
N
I
K
N
L
S
E
E
K
R
E
G
L
Chicken
Gallus gallus
XP_419536
428
49027
C118
K
L
L
R
Q
S
A
C
L
S
E
R
L
Y
S
Frog
Xenopus laevis
NP_001085463
478
54748
L116
I
E
R
E
G
G
G
L
T
E
G
C
L
V
S
Zebra Danio
Brachydanio rerio
NP_001032477
380
43072
S118
K
L
L
S
Q
S
E
S
D
Q
E
E
L
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83501
448
51094
C155
R
I
L
S
V
V
R
C
F
F
L
D
E
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
S116
Q
N
L
E
H
H
P
S
S
Y
D
A
D
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
L129
N
L
Q
N
E
K
V
L
P
I
T
T
T
D
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
99.3
58.1
N.A.
93.9
32
N.A.
59.5
57.9
28.8
42
N.A.
20
N.A.
25.8
N.A.
Protein Similarity:
100
93.8
99.3
60.9
N.A.
96.7
54.2
N.A.
76.1
76.4
50.6
58.4
N.A.
39.7
N.A.
41.4
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
33.3
N.A.
13.3
46.6
20
46.6
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
86.6
53.3
N.A.
33.3
66.6
26.6
73.3
N.A.
26.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
8
0
0
0
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
8
8
0
0
0
% C
% Asp:
0
0
0
31
0
0
0
0
8
0
8
8
8
8
0
% D
% Glu:
8
8
0
16
16
8
8
0
39
16
54
8
16
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
31
8
8
0
0
0
8
0
0
8
0
% G
% His:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
0
0
0
0
0
16
0
0
0
0
0
% I
% Lys:
47
8
0
8
8
24
0
0
0
0
8
39
0
0
0
% K
% Leu:
0
62
31
0
0
0
8
16
8
0
8
0
62
8
8
% L
% Met:
0
0
39
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
8
0
8
0
0
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
0
8
0
39
0
16
0
0
0
0
0
0
% P
% Gln:
16
0
8
0
16
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
16
8
0
0
16
0
0
0
0
16
0
0
0
% R
% Ser:
0
8
0
16
0
16
0
54
8
47
0
0
0
0
62
% S
% Thr:
0
0
0
0
0
8
0
8
8
0
8
8
8
0
8
% T
% Val:
8
0
0
0
8
8
8
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _