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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD3
All Species:
20.91
Human Site:
S409
Identified Species:
38.33
UniProt:
Q9H7B4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7B4
NP_073580.1
428
49097
S409
V
T
H
G
R
E
H
S
L
I
E
D
L
I
L
Chimpanzee
Pan troglodytes
XP_514316
454
52196
S435
V
T
H
G
R
E
H
S
L
I
E
D
L
I
L
Rhesus Macaque
Macaca mulatta
XP_001089022
428
49069
S409
V
T
H
G
R
E
H
S
L
I
E
D
L
I
L
Dog
Lupus familis
XP_537223
266
30635
L252
E
H
S
L
I
E
D
L
I
L
L
L
E
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWR2
428
49108
S409
V
T
H
G
R
E
H
S
L
I
E
D
L
I
L
Rat
Rattus norvegicus
Q7M6Z3
433
49630
A404
N
K
A
A
G
E
K
A
L
K
K
A
I
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513395
408
46852
S376
V
T
H
G
R
R
H
S
L
T
E
E
L
L
T
Chicken
Gallus gallus
XP_419536
428
49027
S409
V
T
H
G
T
D
H
S
L
M
Q
A
L
M
D
Frog
Xenopus laevis
NP_001085463
478
54748
P415
I
T
H
G
P
S
H
P
I
T
K
D
L
E
M
Zebra Danio
Brachydanio rerio
NP_001032477
380
43072
A361
V
T
H
G
A
A
H
A
L
T
N
Q
V
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83501
448
51094
V425
M
D
R
Y
R
E
E
V
L
A
I
L
H
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
M413
K
I
Y
T
P
D
S
M
I
C
R
N
V
Y
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
P456
I
S
H
G
I
S
T
P
F
M
K
E
L
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
99.3
58.1
N.A.
93.9
32
N.A.
59.5
57.9
28.8
42
N.A.
20
N.A.
25.8
N.A.
Protein Similarity:
100
93.8
99.3
60.9
N.A.
96.7
54.2
N.A.
76.1
76.4
50.6
58.4
N.A.
39.7
N.A.
41.4
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
13.3
N.A.
66.6
53.3
40
40
N.A.
26.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
40
N.A.
80
80
66.6
53.3
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
0
16
0
8
0
16
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% C
% Asp:
0
8
0
0
0
16
8
0
0
0
0
39
0
0
8
% D
% Glu:
8
0
0
0
0
54
8
0
0
0
39
16
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
70
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
70
0
0
0
62
0
0
0
0
0
8
0
0
% H
% Ile:
16
8
0
0
16
0
0
0
24
31
8
0
8
31
8
% I
% Lys:
8
8
0
0
0
0
8
0
0
8
24
0
0
8
0
% K
% Leu:
0
0
0
8
0
0
0
8
70
8
8
16
62
8
39
% L
% Met:
8
0
0
0
0
0
0
8
0
16
0
0
0
8
8
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
16
0
0
16
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% Q
% Arg:
0
0
8
0
47
8
0
0
0
0
8
0
0
0
8
% R
% Ser:
0
8
8
0
0
16
8
47
0
0
0
0
0
8
0
% S
% Thr:
0
62
0
8
8
0
8
0
0
24
0
0
0
0
8
% T
% Val:
54
0
0
0
0
0
0
8
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _