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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD3
All Species:
8.79
Human Site:
T22
Identified Species:
16.11
UniProt:
Q9H7B4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7B4
NP_073580.1
428
49097
T22
G
N
G
L
R
A
V
T
P
L
R
P
G
E
L
Chimpanzee
Pan troglodytes
XP_514316
454
52196
T22
G
N
G
L
R
A
V
T
P
L
R
P
G
E
L
Rhesus Macaque
Macaca mulatta
XP_001089022
428
49069
T22
G
N
G
L
R
A
V
T
A
L
R
P
G
E
L
Dog
Lupus familis
XP_537223
266
30635
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWR2
428
49108
A22
G
N
G
L
R
A
V
A
P
L
R
P
G
E
L
Rat
Rattus norvegicus
Q7M6Z3
433
49630
R25
G
R
G
L
R
A
L
R
P
F
H
V
G
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513395
408
46852
R19
E
W
G
F
G
E
W
R
E
K
G
N
E
N
L
Chicken
Gallus gallus
XP_419536
428
49027
R22
G
S
G
L
R
S
R
R
Q
V
R
P
G
E
L
Frog
Xenopus laevis
NP_001085463
478
54748
R20
G
R
G
L
R
A
T
R
E
S
W
A
G
D
V
Zebra Danio
Brachydanio rerio
NP_001032477
380
43072
R22
G
N
G
L
R
A
L
R
E
I
K
P
G
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83501
448
51094
R60
G
R
G
I
F
A
T
R
E
I
A
A
G
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
E23
A
L
A
R
D
Q
V
E
S
Y
C
N
Q
C
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
R29
G
R
S
L
F
T
A
R
D
F
R
P
G
E
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
99.3
58.1
N.A.
93.9
32
N.A.
59.5
57.9
28.8
42
N.A.
20
N.A.
25.8
N.A.
Protein Similarity:
100
93.8
99.3
60.9
N.A.
96.7
54.2
N.A.
76.1
76.4
50.6
58.4
N.A.
39.7
N.A.
41.4
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
93.3
53.3
N.A.
13.3
60
40
60
N.A.
33.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
0
N.A.
93.3
66.6
N.A.
13.3
80
53.3
86.6
N.A.
46.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
62
8
8
8
0
8
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
0
0
0
0
16
0
% D
% Glu:
8
0
0
0
0
8
0
8
31
0
0
0
8
62
8
% E
% Phe:
0
0
0
8
16
0
0
0
0
16
0
0
0
0
0
% F
% Gly:
77
0
77
0
8
0
0
0
0
0
8
0
77
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
16
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% K
% Leu:
0
8
0
70
0
0
16
0
0
31
0
0
0
0
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
39
0
0
0
0
0
0
0
0
0
16
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
31
0
0
54
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
31
0
8
62
0
8
54
0
0
47
0
0
0
0
% R
% Ser:
0
8
8
0
0
8
0
0
8
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
16
24
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
39
0
0
8
0
8
0
0
24
% V
% Trp:
0
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _