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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD3
All Species:
16.67
Human Site:
T277
Identified Species:
30.56
UniProt:
Q9H7B4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7B4
NP_073580.1
428
49097
T277
D
K
D
A
D
M
L
T
G
D
E
Q
V
W
K
Chimpanzee
Pan troglodytes
XP_514316
454
52196
T303
D
K
D
A
D
M
L
T
G
D
E
Q
V
W
K
Rhesus Macaque
Macaca mulatta
XP_001089022
428
49069
T277
D
K
D
A
D
M
L
T
G
D
E
Q
V
W
K
Dog
Lupus familis
XP_537223
266
30635
N162
A
E
R
L
P
D
I
N
V
Y
Q
L
R
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWR2
428
49108
T277
D
K
D
A
D
M
L
T
G
D
E
Q
I
W
K
Rat
Rattus norvegicus
Q7M6Z3
433
49630
E278
D
K
D
K
A
K
V
E
I
R
K
L
S
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513395
408
46852
K254
E
P
F
W
K
E
V
K
D
A
V
D
T
V
E
Chicken
Gallus gallus
XP_419536
428
49027
A277
E
K
D
A
K
K
L
A
G
E
E
P
A
W
K
Frog
Xenopus laevis
NP_001085463
478
54748
A272
T
K
D
A
L
L
L
A
V
N
D
G
E
S
K
Zebra Danio
Brachydanio rerio
NP_001032477
380
43072
D270
A
L
L
H
R
H
S
D
V
V
P
D
R
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83501
448
51094
S310
T
E
N
G
T
Y
L
S
A
L
F
C
R
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
T276
Q
C
E
L
C
G
W
T
M
S
K
D
H
F
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
E285
G
K
P
H
D
I
E
E
S
A
I
L
E
G
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
99.3
58.1
N.A.
93.9
32
N.A.
59.5
57.9
28.8
42
N.A.
20
N.A.
25.8
N.A.
Protein Similarity:
100
93.8
99.3
60.9
N.A.
96.7
54.2
N.A.
76.1
76.4
50.6
58.4
N.A.
39.7
N.A.
41.4
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
20
N.A.
0
53.3
33.3
0
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
33.3
N.A.
20
66.6
53.3
0
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
47
8
0
0
16
8
16
0
0
8
0
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
39
0
54
0
39
8
0
8
8
31
8
24
0
0
0
% D
% Glu:
16
16
8
0
0
8
8
16
0
8
39
0
16
8
16
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
8
0
0
8
0
8
0
0
39
0
0
8
0
8
0
% G
% His:
0
0
0
16
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
8
0
8
0
8
0
8
% I
% Lys:
0
62
0
8
16
16
0
8
0
0
16
0
0
0
47
% K
% Leu:
0
8
8
16
8
8
54
0
0
8
0
24
0
0
8
% L
% Met:
0
0
0
0
0
31
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
8
0
0
0
16
0
% N
% Pro:
0
8
8
0
8
0
0
0
0
0
8
8
0
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
8
31
0
0
8
% Q
% Arg:
0
0
8
0
8
0
0
0
0
8
0
0
24
0
0
% R
% Ser:
0
0
0
0
0
0
8
8
8
8
0
0
8
8
0
% S
% Thr:
16
0
0
0
8
0
0
39
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
16
0
24
8
8
0
24
16
0
% V
% Trp:
0
0
0
8
0
0
8
0
0
0
0
0
0
39
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _