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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD3
All Species:
25.45
Human Site:
Y350
Identified Species:
46.67
UniProt:
Q9H7B4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7B4
NP_073580.1
428
49097
Y350
L
L
E
E
A
L
F
Y
G
T
R
T
M
E
P
Chimpanzee
Pan troglodytes
XP_514316
454
52196
Y376
L
L
E
E
A
L
F
Y
A
T
R
T
M
E
P
Rhesus Macaque
Macaca mulatta
XP_001089022
428
49069
Y350
L
L
E
E
A
L
F
Y
G
T
R
T
M
E
P
Dog
Lupus familis
XP_537223
266
30635
K216
V
Q
V
M
K
V
G
K
L
Q
L
H
Q
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWR2
428
49108
Y350
M
L
E
E
A
L
F
Y
A
M
R
T
M
E
P
Rat
Rattus norvegicus
Q7M6Z3
433
49630
Y362
D
W
E
G
A
L
K
Y
G
Q
K
I
I
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513395
408
46852
Y317
L
W
E
D
A
L
L
Y
G
R
R
T
L
D
P
Chicken
Gallus gallus
XP_419536
428
49027
Y350
A
W
E
Q
A
L
C
Y
G
S
R
T
L
G
P
Frog
Xenopus laevis
NP_001085463
478
54748
N356
M
F
Q
D
A
A
E
N
A
K
K
M
I
D
G
Zebra Danio
Brachydanio rerio
NP_001032477
380
43072
L325
H
P
S
R
A
V
E
L
L
R
V
G
K
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83501
448
51094
D371
I
N
S
C
S
V
Q
D
M
I
H
F
I
N
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
T354
N
I
T
A
A
A
K
T
G
G
T
L
L
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
Y397
I
W
R
E
A
L
N
Y
C
R
L
I
V
P
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
99.3
58.1
N.A.
93.9
32
N.A.
59.5
57.9
28.8
42
N.A.
20
N.A.
25.8
N.A.
Protein Similarity:
100
93.8
99.3
60.9
N.A.
96.7
54.2
N.A.
76.1
76.4
50.6
58.4
N.A.
39.7
N.A.
41.4
N.A.
P-Site Identity:
100
93.3
100
0
N.A.
80
40
N.A.
60
53.3
6.6
6.6
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
93.3
100
13.3
N.A.
86.6
60
N.A.
80
73.3
46.6
13.3
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
85
16
0
0
24
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
16
0
0
0
8
0
0
0
0
0
16
0
% D
% Glu:
0
0
54
39
0
0
16
0
0
0
0
0
0
31
8
% E
% Phe:
0
8
0
0
0
0
31
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
47
8
0
8
0
16
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
16
8
0
0
0
0
0
0
0
8
0
16
24
0
8
% I
% Lys:
0
0
0
0
8
0
16
8
0
8
16
0
8
8
0
% K
% Leu:
31
31
0
0
0
62
8
8
16
0
16
8
24
8
0
% L
% Met:
16
0
0
8
0
0
0
0
8
8
0
8
31
0
8
% M
% Asn:
8
8
0
0
0
0
8
8
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
54
% P
% Gln:
0
8
8
8
0
0
8
0
0
16
0
0
8
0
8
% Q
% Arg:
0
0
8
8
0
0
0
0
0
24
47
0
0
0
0
% R
% Ser:
0
0
16
0
8
0
0
0
0
8
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
8
0
24
8
47
0
0
0
% T
% Val:
8
0
8
0
0
24
0
0
0
0
8
0
8
0
8
% V
% Trp:
0
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _