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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMYD3 All Species: 16.36
Human Site: Y38 Identified Species: 30
UniProt: Q9H7B4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7B4 NP_073580.1 428 49097 Y38 F R S D P L A Y T V C K G S R
Chimpanzee Pan troglodytes XP_514316 454 52196 Y38 F R S D P L A Y T V C K G S R
Rhesus Macaque Macaca mulatta XP_001089022 428 49069 Y38 F R S D P L A Y T V C K G S R
Dog Lupus familis XP_537223 266 30635
Cat Felis silvestris
Mouse Mus musculus Q9CWR2 428 49108 Y38 F R S D P L A Y T V C K G S R
Rat Rattus norvegicus Q7M6Z3 433 49630 C41 F S C P A Y A C V L T V G E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513395 408 46852 A35 R C S R C K V A R Y C G L V C
Chicken Gallus gallus XP_419536 428 49027 Y38 Y R A E P F A Y V V T K E Q L
Frog Xenopus laevis NP_001085463 478 54748 A36 F A E P A Y S A V V F D N L S
Zebra Danio Brachydanio rerio NP_001032477 380 43072 F38 Y S C E P F A F C V A R D F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P83501 448 51094 V76 F R E H T L L V G P T A H R S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09415 429 48527 C39 S M A E L K K C S A C R R L A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7XJS0 480 54809 C45 L S Q K P Y I C V P N N T S S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 99.3 58.1 N.A. 93.9 32 N.A. 59.5 57.9 28.8 42 N.A. 20 N.A. 25.8 N.A.
Protein Similarity: 100 93.8 99.3 60.9 N.A. 96.7 54.2 N.A. 76.1 76.4 50.6 58.4 N.A. 39.7 N.A. 41.4 N.A.
P-Site Identity: 100 100 100 0 N.A. 100 26.6 N.A. 13.3 40 13.3 20 N.A. 20 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 0 N.A. 100 33.3 N.A. 13.3 60 20 46.6 N.A. 20 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 0 16 0 54 16 0 8 8 8 0 0 8 % A
% Cys: 0 8 16 0 8 0 0 24 8 0 47 0 0 0 8 % C
% Asp: 0 0 0 31 0 0 0 0 0 0 0 8 8 0 0 % D
% Glu: 0 0 16 24 0 0 0 0 0 0 0 0 8 8 0 % E
% Phe: 54 0 0 0 0 16 0 8 0 0 8 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 8 39 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 16 8 0 0 0 0 39 0 0 0 % K
% Leu: 8 0 0 0 8 39 8 0 0 8 0 0 8 16 16 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 8 8 0 0 % N
% Pro: 0 0 0 16 54 0 0 0 0 16 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 47 0 8 0 0 0 0 8 0 0 16 8 8 39 % R
% Ser: 8 24 39 0 0 0 8 0 8 0 0 0 0 39 24 % S
% Thr: 0 0 0 0 8 0 0 0 31 0 24 0 8 0 0 % T
% Val: 0 0 0 0 0 0 8 8 31 54 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 0 24 0 39 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _