KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOCK5
All Species:
21.52
Human Site:
S251
Identified Species:
67.62
UniProt:
Q9H7D0
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7D0
NP_079216.4
1870
215309
S251
A
L
Y
D
P
D
Q
S
T
F
I
S
E
N
Y
Chimpanzee
Pan troglodytes
XP_519666
1870
215238
S251
A
L
Y
D
P
D
Q
S
T
F
I
S
E
N
Y
Rhesus Macaque
Macaca mulatta
XP_001107224
1870
215340
S251
A
L
Y
D
P
D
Q
S
T
F
I
S
E
N
Y
Dog
Lupus familis
XP_544064
1858
214527
S242
S
L
Y
D
P
V
E
S
K
F
I
S
E
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
B2RY04
1868
214496
S251
A
L
Y
D
P
D
Q
S
T
F
I
S
E
N
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508993
1829
212107
Q244
S
L
Y
D
P
N
K
Q
T
V
I
S
E
N
Y
Chicken
Gallus gallus
XP_417678
1877
216176
S251
S
L
Y
D
P
D
L
S
K
F
I
S
E
N
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785550
1874
216318
C253
S
L
Y
D
G
K
L
C
E
H
I
S
E
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.9
64
N.A.
93.9
N.A.
N.A.
54.3
86.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.2
Protein Similarity:
100
99.9
99.5
78.6
N.A.
97.2
N.A.
N.A.
70.6
93.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
63.9
P-Site Identity:
100
100
100
73.3
N.A.
100
N.A.
N.A.
66.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
N.A.
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
100
0
63
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
13
0
13
0
0
0
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% I
% Lys:
0
0
0
0
0
13
13
0
25
0
0
0
0
0
0
% K
% Leu:
0
100
0
0
0
0
25
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
88
0
% N
% Pro:
0
0
0
0
88
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
13
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
0
0
0
0
0
0
75
0
0
0
100
0
13
0
% S
% Thr:
0
0
0
0
0
0
0
0
63
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
13
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
100
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _