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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM185B
All Species:
21.21
Human Site:
S311
Identified Species:
38.89
UniProt:
Q9H7F4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7F4
NP_115897
350
40599
S311
S
E
D
A
E
E
T
S
V
P
E
A
P
K
I
Chimpanzee
Pan troglodytes
XP_525903
350
40581
S311
S
E
D
A
E
E
T
S
V
P
E
A
P
K
I
Rhesus Macaque
Macaca mulatta
XP_001084745
350
40565
S311
S
E
D
A
E
E
T
S
V
P
E
A
P
K
I
Dog
Lupus familis
XP_533320
350
40576
S311
S
E
D
A
E
E
T
S
V
P
D
A
P
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3R5
350
40683
S311
S
E
D
A
E
D
A
S
V
S
E
A
P
K
I
Rat
Rattus norvegicus
XP_222559
350
40599
S311
S
E
D
A
E
D
A
S
A
L
E
A
P
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512605
467
52814
P428
N
E
E
T
E
E
T
P
V
P
E
P
P
K
I
Chicken
Gallus gallus
XP_420360
366
42483
P327
N
E
E
A
E
E
T
P
V
P
E
P
P
K
I
Frog
Xenopus laevis
NP_001089386
351
40616
P312
S
E
D
A
E
E
T
P
V
P
E
P
A
K
I
Zebra Danio
Brachydanio rerio
Q7SYC7
351
40665
P312
S
D
M
S
E
E
L
P
I
H
E
V
P
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573360
358
40655
L311
N
A
A
Q
S
M
P
L
D
A
A
S
S
S
T
Honey Bee
Apis mellifera
XP_396742
339
39216
M311
D
Q
P
P
S
E
P
M
V
S
E
K
N
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203000
345
39695
I317
Q
E
P
E
E
Q
E
I
Q
R
E
I
Y
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99.4
97.1
N.A.
96
96.2
N.A.
66.3
82.5
86.6
82.9
N.A.
45.5
51.7
N.A.
54.2
Protein Similarity:
100
100
99.7
98.8
N.A.
98.2
98.2
N.A.
71
89
92.3
90.3
N.A.
63.9
70.2
N.A.
73.4
P-Site Identity:
100
100
100
93.3
N.A.
80
73.3
N.A.
66.6
73.3
80
46.6
N.A.
0
20
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
80
86.6
80
66.6
N.A.
13.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
62
0
0
16
0
8
8
8
47
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
54
0
0
16
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
77
16
8
85
70
8
0
0
0
85
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
8
8
0
0
8
0
8
77
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
0
77
8
% K
% Leu:
0
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% L
% Met:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
24
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
16
8
0
0
16
31
0
54
0
24
70
0
0
% P
% Gln:
8
8
0
8
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
62
0
0
8
16
0
0
47
0
16
0
8
8
8
0
% S
% Thr:
0
0
0
8
0
0
54
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
70
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _