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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM185B
All Species:
42.73
Human Site:
T260
Identified Species:
78.33
UniProt:
Q9H7F4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7F4
NP_115897
350
40599
T260
S
L
L
T
L
M
A
T
T
F
R
R
K
G
G
Chimpanzee
Pan troglodytes
XP_525903
350
40581
T260
S
L
L
T
L
M
A
T
T
F
R
R
K
G
G
Rhesus Macaque
Macaca mulatta
XP_001084745
350
40565
T260
S
L
L
T
L
M
A
T
T
F
R
R
K
G
G
Dog
Lupus familis
XP_533320
350
40576
T260
S
L
I
T
L
M
A
T
T
F
R
R
K
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3R5
350
40683
T260
S
L
L
T
L
M
A
T
T
F
R
R
K
G
G
Rat
Rattus norvegicus
XP_222559
350
40599
T260
S
L
L
T
L
M
A
T
T
F
R
R
K
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512605
467
52814
T377
S
L
I
T
L
M
A
T
T
F
G
Q
K
G
G
Chicken
Gallus gallus
XP_420360
366
42483
T276
S
L
I
T
L
M
A
T
T
F
G
Q
K
G
G
Frog
Xenopus laevis
NP_001089386
351
40616
T261
S
L
I
T
L
M
A
T
T
F
G
Q
K
G
G
Zebra Danio
Brachydanio rerio
Q7SYC7
351
40665
T261
S
L
V
T
L
M
V
T
T
F
G
Q
K
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573360
358
40655
L260
S
I
L
A
L
I
V
L
S
S
S
A
K
G
G
Honey Bee
Apis mellifera
XP_396742
339
39216
M260
S
H
I
T
L
I
F
M
S
F
D
A
K
G
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203000
345
39695
T266
S
L
L
V
L
L
P
T
A
F
G
Q
R
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99.4
97.1
N.A.
96
96.2
N.A.
66.3
82.5
86.6
82.9
N.A.
45.5
51.7
N.A.
54.2
Protein Similarity:
100
100
99.7
98.8
N.A.
98.2
98.2
N.A.
71
89
92.3
90.3
N.A.
63.9
70.2
N.A.
73.4
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
80
80
80
73.3
N.A.
40
46.6
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
60
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
70
0
8
0
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
93
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
39
0
0
100
100
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
39
0
0
16
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% K
% Leu:
0
85
54
0
100
8
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
77
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
47
47
8
0
0
% R
% Ser:
100
0
0
0
0
0
0
0
16
8
8
0
0
0
0
% S
% Thr:
0
0
0
85
0
0
0
85
77
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
16
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _