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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM185B
All Species:
39.39
Human Site:
Y337
Identified Species:
72.22
UniProt:
Q9H7F4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7F4
NP_115897
350
40599
Y337
I
T
Q
S
P
G
K
Y
V
P
P
P
P
K
L
Chimpanzee
Pan troglodytes
XP_525903
350
40581
Y337
I
T
Q
S
P
G
K
Y
V
P
P
P
P
K
L
Rhesus Macaque
Macaca mulatta
XP_001084745
350
40565
Y337
I
T
Q
S
P
G
K
Y
V
P
P
P
P
K
L
Dog
Lupus familis
XP_533320
350
40576
Y337
I
T
Q
S
P
G
K
Y
V
P
P
P
P
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3R5
350
40683
Y337
I
T
Q
S
P
G
K
Y
V
P
P
P
P
K
L
Rat
Rattus norvegicus
XP_222559
350
40599
Y337
I
T
Q
S
P
G
K
Y
V
P
P
P
P
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512605
467
52814
Y454
I
T
Q
S
P
G
K
Y
V
I
P
P
P
K
L
Chicken
Gallus gallus
XP_420360
366
42483
Y353
I
T
Q
S
P
G
K
Y
V
I
P
P
P
K
L
Frog
Xenopus laevis
NP_001089386
351
40616
Y338
I
T
Q
S
P
G
K
Y
V
V
P
P
P
K
L
Zebra Danio
Brachydanio rerio
Q7SYC7
351
40665
Y338
I
T
Q
S
P
G
K
Y
F
V
P
P
P
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573360
358
40655
P347
A
K
N
D
I
L
K
P
V
V
P
F
V
S
I
Honey Bee
Apis mellifera
XP_396742
339
39216
I332
L
T
K
P
V
V
P
I
I
S
I
D
M
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203000
345
39695
V338
D
Y
K
V
V
M
P
V
I
S
I
D
T
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99.4
97.1
N.A.
96
96.2
N.A.
66.3
82.5
86.6
82.9
N.A.
45.5
51.7
N.A.
54.2
Protein Similarity:
100
100
99.7
98.8
N.A.
98.2
98.2
N.A.
71
89
92.3
90.3
N.A.
63.9
70.2
N.A.
73.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
26.6
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
0
0
16
0
0
16
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
77
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
77
0
0
0
8
0
0
8
16
16
16
0
0
0
8
% I
% Lys:
0
8
16
0
0
0
85
0
0
0
0
0
0
77
0
% K
% Leu:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
77
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
77
0
16
8
0
47
85
77
77
16
0
% P
% Gln:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
77
0
0
0
0
0
16
0
0
0
8
0
% S
% Thr:
0
85
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
8
16
8
0
8
77
24
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _