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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METT11D1 All Species: 18.48
Human Site: T278 Identified Species: 36.97
UniProt: Q9H7H0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7H0 NP_001025162.1 456 50734 T278 L P S K A D R T E V V Q T L W
Chimpanzee Pan troglodytes XP_001142880 456 50682 T278 L P S K A D R T E V V Q T L W
Rhesus Macaque Macaca mulatta XP_001093161 459 51400 T278 L P S R A D R T E V V Q T L W
Dog Lupus familis XP_532619 366 40994 R210 H C L L M D A R D L V L K G K
Cat Felis silvestris
Mouse Mus musculus Q3U2U7 461 52003 I279 L P S R A D R I E V I Q N L W
Rat Rattus norvegicus XP_223974 461 52043 T279 L P S R A D R T E V L Q N L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521559 441 48968 S265 L P S L A A R S E V V S T L W
Chicken Gallus gallus
Frog Xenopus laevis NP_001085539 456 51967 E271 L P S L S E R E K I I H A L W
Zebra Danio Brachydanio rerio XP_688882 431 49606 L257 L A T L D E R L N V I S T L W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609330 463 53696 D282 E N K E Q R E D V L R N L W R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493592 529 60285 L302 I G S S E T R L Q L I E S L W
Sea Urchin Strong. purpuratus XP_788426 354 40529 S198 L M E S Q D Q S E D S S N A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.9 67.3 N.A. 79.6 81.1 N.A. 67.3 N.A. 55.2 45.8 N.A. 33 N.A. 25.8 25.4
Protein Similarity: 100 99.7 96.5 72.1 N.A. 87.1 87.4 N.A. 77.1 N.A. 71.7 62.7 N.A. 53.3 N.A. 42.9 41
P-Site Identity: 100 100 93.3 13.3 N.A. 73.3 80 N.A. 73.3 N.A. 40 40 N.A. 0 N.A. 26.6 20
P-Site Similarity: 100 100 100 26.6 N.A. 86.6 93.3 N.A. 80 N.A. 73.3 60 N.A. 13.3 N.A. 66.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 50 9 9 0 0 0 0 0 9 9 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 59 0 9 9 9 0 0 0 0 0 % D
% Glu: 9 0 9 9 9 17 9 9 59 0 0 9 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 9 0 9 34 0 0 0 0 % I
% Lys: 0 0 9 17 0 0 0 0 9 0 0 0 9 0 9 % K
% Leu: 75 0 9 34 0 0 0 17 0 25 9 9 9 75 0 % L
% Met: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 9 0 0 9 25 0 0 % N
% Pro: 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 17 0 9 0 9 0 0 42 0 0 0 % Q
% Arg: 0 0 0 25 0 9 75 9 0 0 9 0 0 0 9 % R
% Ser: 0 0 67 17 9 0 0 17 0 0 9 25 9 0 0 % S
% Thr: 0 0 9 0 0 9 0 34 0 0 0 0 42 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 59 42 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 75 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _