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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METT11D1 All Species: 18.18
Human Site: T389 Identified Species: 36.36
UniProt: Q9H7H0 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7H0 NP_001025162.1 456 50734 T389 A H R W P R I T Q P V L K R P
Chimpanzee Pan troglodytes XP_001142880 456 50682 T389 A N R W P R I T Q P V L K R P
Rhesus Macaque Macaca mulatta XP_001093161 459 51400 T392 A N R W P R I T Q P V L R R P
Dog Lupus familis XP_532619 366 40994 G312 C H L C C P D G H M Q H A V I
Cat Felis silvestris
Mouse Mus musculus Q3U2U7 461 52003 T393 A N R W P R I T Q P V L K R P
Rat Rattus norvegicus XP_223974 461 52043 T393 A N R W P R I T Q P V L K R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521559 441 48968 I379 G Q R W S R V I Q P V L K R P
Chicken Gallus gallus
Frog Xenopus laevis NP_001085539 456 51967 V385 G D G H W P R V I S H V L S R
Zebra Danio Brachydanio rerio XP_688882 431 49606 D371 A Q K A E H W D M A R V I A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609330 463 53696 R393 S S W P R I V R P T L V R S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493592 529 60285 N460 K S Q R K V N N E H T E R I L
Sea Urchin Strong. purpuratus XP_788426 354 40529 R300 K P V L K K S R H I I C R L C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.9 67.3 N.A. 79.6 81.1 N.A. 67.3 N.A. 55.2 45.8 N.A. 33 N.A. 25.8 25.4
Protein Similarity: 100 99.7 96.5 72.1 N.A. 87.1 87.4 N.A. 77.1 N.A. 71.7 62.7 N.A. 53.3 N.A. 42.9 41
P-Site Identity: 100 93.3 86.6 6.6 N.A. 93.3 93.3 N.A. 66.6 N.A. 0 6.6 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 73.3 N.A. 6.6 20 N.A. 33.3 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 9 0 0 0 0 0 9 0 0 9 9 0 % A
% Cys: 9 0 0 9 9 0 0 0 0 0 0 9 0 0 9 % C
% Asp: 0 9 0 0 0 0 9 9 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 9 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 17 0 9 0 9 0 0 17 9 9 9 0 0 0 % H
% Ile: 0 0 0 0 0 9 42 9 9 9 9 0 9 9 9 % I
% Lys: 17 0 9 0 17 9 0 0 0 0 0 0 42 0 9 % K
% Leu: 0 0 9 9 0 0 0 0 0 0 9 50 9 9 9 % L
% Met: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % M
% Asn: 0 34 0 0 0 0 9 9 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 9 42 17 0 0 9 50 0 0 0 0 50 % P
% Gln: 0 17 9 0 0 0 0 0 50 0 9 0 0 0 9 % Q
% Arg: 0 0 50 9 9 50 9 17 0 0 9 0 34 50 9 % R
% Ser: 9 17 0 0 9 0 9 0 0 9 0 0 0 17 0 % S
% Thr: 0 0 0 0 0 0 0 42 0 9 9 0 0 0 0 % T
% Val: 0 0 9 0 0 9 17 9 0 0 50 25 0 9 0 % V
% Trp: 0 0 9 50 9 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _