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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R3E
All Species:
23.64
Human Site:
S66
Identified Species:
52
UniProt:
Q9H7J1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7J1
NP_006233
279
30644
S66
S
R
G
R
R
A
R
S
A
P
A
G
G
G
G
Chimpanzee
Pan troglodytes
XP_509850
255
27918
S66
S
R
G
R
R
A
R
S
A
P
A
G
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001102470
274
30154
S66
S
R
G
R
R
A
R
S
A
P
A
G
G
G
G
Dog
Lupus familis
XP_547732
279
30602
S66
S
R
G
R
R
A
L
S
A
P
A
G
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRJ4
279
30556
S66
G
R
G
R
R
A
R
S
A
P
A
G
G
G
G
Rat
Rattus norvegicus
P0C7L8
279
30605
S66
G
R
G
R
R
A
R
S
A
P
A
G
G
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511700
305
33609
R81
S
L
P
S
S
P
E
R
R
K
K
A
A
G
G
Chicken
Gallus gallus
XP_417397
303
34691
S82
I
I
R
R
R
A
R
S
L
P
T
T
P
E
R
Frog
Xenopus laevis
NP_001089324
247
27899
R70
T
R
R
P
P
D
P
R
K
K
N
V
V
F
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500391
318
35618
F81
Q
S
V
K
R
V
R
F
A
D
S
L
G
L
D
Sea Urchin
Strong. purpuratus
XP_783512
425
46821
I264
D
L
E
T
V
R
H
I
L
E
M
D
P
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
96.4
96
N.A.
89.6
88.8
N.A.
35.7
31.6
28.3
N.A.
N.A.
N.A.
N.A.
25.7
23.2
Protein Similarity:
100
84.9
97.1
96.7
N.A.
91.7
91.4
N.A.
48.5
49.5
41.5
N.A.
N.A.
N.A.
N.A.
38.9
34.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
40
6.6
N.A.
N.A.
N.A.
N.A.
26.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
40
13.3
N.A.
N.A.
N.A.
N.A.
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
64
0
0
64
0
55
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
0
0
0
10
0
0
0
10
0
10
0
0
10
% D
% Glu:
0
0
10
0
0
0
10
0
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
19
0
55
0
0
0
0
0
0
0
0
55
64
64
64
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
19
10
0
0
0
0
% K
% Leu:
0
19
0
0
0
0
10
0
19
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
10
10
10
10
0
0
64
0
0
19
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
64
19
64
73
10
64
19
10
0
0
0
0
0
10
% R
% Ser:
46
10
0
10
10
0
0
64
0
0
10
0
0
0
0
% S
% Thr:
10
0
0
10
0
0
0
0
0
0
10
10
0
0
0
% T
% Val:
0
0
10
0
10
10
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _