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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZSWIM4
All Species:
21.82
Human Site:
S142
Identified Species:
53.33
UniProt:
Q9H7M6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7M6
NP_075560.2
989
110168
S142
P
E
R
L
Y
H
V
S
I
S
F
D
R
C
K
Chimpanzee
Pan troglodytes
XP_524448
1095
121462
S248
P
E
R
L
Y
H
V
S
I
S
F
D
R
C
K
Rhesus Macaque
Macaca mulatta
XP_001111031
1102
122485
S142
P
E
R
L
Y
H
V
S
I
S
F
D
R
C
K
Dog
Lupus familis
XP_867133
989
109865
S142
P
E
R
L
Y
H
V
S
I
S
F
D
R
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7B8
1101
122426
S137
P
E
H
L
Y
H
V
S
I
S
F
D
R
C
K
Rat
Rattus norvegicus
NP_001100633
912
101165
Q128
R
L
A
L
W
R
Q
Q
G
A
A
M
T
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422431
1110
122366
A147
P
E
M
T
Y
K
V
A
I
S
F
D
R
C
K
Frog
Xenopus laevis
NP_001084576
1092
121651
S126
P
E
R
T
Y
Q
V
S
I
S
F
D
R
C
K
Zebra Danio
Brachydanio rerio
NP_001138291
1151
128439
A190
P
E
T
T
H
K
V
A
I
S
F
D
R
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789113
983
110838
G154
V
K
L
Y
L
Q
Q
G
S
Y
Y
D
S
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
85.3
96.5
N.A.
83.7
62.8
N.A.
N.A.
58.3
70.4
60.6
N.A.
N.A.
N.A.
N.A.
40.3
Protein Similarity:
100
90
86.2
97.7
N.A.
85.7
70.1
N.A.
N.A.
69.2
79.5
71.9
N.A.
N.A.
N.A.
N.A.
55.4
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
N.A.
73.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
N.A.
80
86.6
80
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
20
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
90
0
10
0
% D
% Glu:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
0
0
0
0
10
0
% G
% His:
0
0
10
0
10
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
20
0
0
0
0
0
0
0
0
100
% K
% Leu:
0
10
10
60
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
20
20
10
0
0
0
0
0
0
0
% Q
% Arg:
10
0
50
0
0
10
0
0
0
0
0
0
80
0
0
% R
% Ser:
0
0
0
0
0
0
0
60
10
80
0
0
10
0
0
% S
% Thr:
0
0
10
30
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
10
0
0
0
0
0
80
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
70
0
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _