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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZSWIM4
All Species:
8.79
Human Site:
S746
Identified Species:
21.48
UniProt:
Q9H7M6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7M6
NP_075560.2
989
110168
S746
L
R
L
Q
L
D
T
S
R
R
E
E
L
W
A
Chimpanzee
Pan troglodytes
XP_524448
1095
121462
S852
L
R
L
Q
L
D
T
S
R
R
E
E
L
W
A
Rhesus Macaque
Macaca mulatta
XP_001111031
1102
122485
P859
L
R
L
Q
L
D
T
P
R
R
E
E
L
W
A
Dog
Lupus familis
XP_867133
989
109865
P746
S
R
L
Q
L
D
A
P
R
R
E
E
L
W
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7B8
1101
122426
A858
L
R
L
Q
L
D
T
A
G
R
E
E
L
W
A
Rat
Rattus norvegicus
NP_001100633
912
101165
T669
L
R
L
Q
L
D
T
T
G
R
E
E
L
W
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422431
1110
122366
P866
L
R
L
S
L
D
Y
P
Q
R
E
E
L
A
S
Frog
Xenopus laevis
NP_001084576
1092
121651
R843
L
R
F
S
P
D
P
R
Q
R
E
E
L
C
S
Zebra Danio
Brachydanio rerio
NP_001138291
1151
128439
P907
L
R
L
S
L
D
Y
P
Q
R
E
E
L
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789113
983
110838
R738
V
R
L
N
L
N
F
R
E
Q
E
E
L
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
85.3
96.5
N.A.
83.7
62.8
N.A.
N.A.
58.3
70.4
60.6
N.A.
N.A.
N.A.
N.A.
40.3
Protein Similarity:
100
90
86.2
97.7
N.A.
85.7
70.1
N.A.
N.A.
69.2
79.5
71.9
N.A.
N.A.
N.A.
N.A.
55.4
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
N.A.
60
46.6
60
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
93.3
80
N.A.
93.3
93.3
N.A.
N.A.
73.3
60
73.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
0
0
0
0
30
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
90
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
100
100
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
80
0
90
0
90
0
0
0
0
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
10
40
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
60
0
0
0
0
30
10
0
0
0
0
0
% Q
% Arg:
0
100
0
0
0
0
0
20
40
90
0
0
0
0
10
% R
% Ser:
10
0
0
30
0
0
0
20
0
0
0
0
0
0
30
% S
% Thr:
0
0
0
0
0
0
50
10
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _