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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZSWIM4
All Species:
15.45
Human Site:
T436
Identified Species:
37.78
UniProt:
Q9H7M6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7M6
NP_075560.2
989
110168
T436
R
L
E
E
E
T
L
T
L
Y
P
D
S
G
P
Chimpanzee
Pan troglodytes
XP_524448
1095
121462
T542
R
L
E
E
E
T
L
T
L
Y
P
D
S
G
P
Rhesus Macaque
Macaca mulatta
XP_001111031
1102
122485
T553
R
L
E
E
E
A
L
T
L
Y
P
D
S
G
P
Dog
Lupus familis
XP_867133
989
109865
A436
R
L
E
E
E
T
L
A
L
Y
P
D
S
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7B8
1101
122426
S548
R
L
E
E
E
P
H
S
L
F
P
D
S
A
P
Rat
Rattus norvegicus
NP_001100633
912
101165
V393
Y
L
A
L
A
L
E
V
A
L
L
G
L
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422431
1110
122366
L553
R
L
E
E
E
N
C
L
E
I
S
D
T
G
D
Frog
Xenopus laevis
NP_001084576
1092
121651
S531
L
P
E
D
E
G
L
S
L
Y
P
D
I
G
G
Zebra Danio
Brachydanio rerio
NP_001138291
1151
128439
D596
V
E
D
D
N
T
M
D
T
G
D
S
G
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789113
983
110838
A432
A
N
P
E
G
L
D
A
S
H
A
N
N
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
85.3
96.5
N.A.
83.7
62.8
N.A.
N.A.
58.3
70.4
60.6
N.A.
N.A.
N.A.
N.A.
40.3
Protein Similarity:
100
90
86.2
97.7
N.A.
85.7
70.1
N.A.
N.A.
69.2
79.5
71.9
N.A.
N.A.
N.A.
N.A.
55.4
P-Site Identity:
100
100
93.3
93.3
N.A.
66.6
13.3
N.A.
N.A.
46.6
53.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
13.3
N.A.
N.A.
53.3
66.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
10
10
0
20
10
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
20
0
0
10
10
0
0
10
70
0
0
10
% D
% Glu:
0
10
70
70
70
0
10
0
10
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
10
0
10
10
70
10
% G
% His:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
70
0
10
0
20
50
10
60
10
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
10
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
10
10
0
0
10
0
0
0
0
60
0
0
0
60
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
20
10
0
10
10
50
0
0
% S
% Thr:
0
0
0
0
0
40
0
30
10
0
0
0
10
0
0
% T
% Val:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
50
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _