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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM125B All Species: 17.88
Human Site: S210 Identified Species: 35.76
UniProt: Q9H7P6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7P6 NP_001011703.1 319 35620 S210 P T T P S Q S S A A S T P A P
Chimpanzee Pan troglodytes XP_001141271 417 45955 S308 P T T P S Q S S A A S T P A P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537843 455 50313 S346 P T T P S Q S S A A S T P A P
Cat Felis silvestris
Mouse Mus musculus Q6KAU4 317 35393 S208 P T T P S Q S S A S S T P A P
Rat Rattus norvegicus Q6P777 271 28734 D163 K P G T L S Q D M R G L S L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508745 413 45132 S304 S T T P S S Q S S A S T P A P
Chicken Gallus gallus Q5ZJX7 267 28044 R159 P P P V P K P R T V S L G L K
Frog Xenopus laevis Q7ZYJ7 275 29879 L167 S G I K G L S L D S N T A V Q
Zebra Danio Brachydanio rerio Q7SXX7 275 29748 S167 S L D I R S L S L D G P A P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera NP_001106142 324 36127 K213 I P P E R P P K P T N G V Y P
Nematode Worm Caenorhab. elegans NP_501302 277 30361 G169 I S I P Q T Y G I Q T S N S T
Sea Urchin Strong. purpuratus XP_786710 276 31108 Q168 A P V P A P R Q N V N Q P Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.5 N.A. 68.1 N.A. 96.2 31.3 N.A. 68.2 29.4 28.8 21.6 N.A. N.A. 25 26.6 31
Protein Similarity: 100 76.5 N.A. 68.7 N.A. 98.1 46 N.A. 72.4 46.7 46.3 34.7 N.A. N.A. 45.3 47.3 46.3
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 0 N.A. 73.3 13.3 13.3 13.3 N.A. N.A. 6.6 6.6 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 0 N.A. 80 20 26.6 13.3 N.A. N.A. 13.3 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 0 0 34 34 0 0 17 42 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 9 9 9 0 0 0 0 9 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 9 0 9 0 0 9 0 0 17 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 17 9 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 9 0 0 9 0 9 0 9 0 0 0 0 0 0 9 % K
% Leu: 0 9 0 0 9 9 9 9 9 0 0 17 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 25 0 9 0 0 % N
% Pro: 42 34 17 59 9 17 17 0 9 0 0 9 50 9 59 % P
% Gln: 0 0 0 0 9 34 17 9 0 9 0 9 0 9 9 % Q
% Arg: 0 0 0 0 17 0 9 9 0 9 0 0 0 0 0 % R
% Ser: 25 9 0 0 42 25 42 50 9 17 50 9 9 9 9 % S
% Thr: 0 42 42 9 0 9 0 0 9 9 9 50 0 0 9 % T
% Val: 0 0 9 9 0 0 0 0 0 17 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _