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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM125B
All Species:
18.79
Human Site:
S224
Identified Species:
37.58
UniProt:
Q9H7P6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7P6
NP_001011703.1
319
35620
S224
P
N
L
P
R
H
I
S
L
T
L
P
A
T
F
Chimpanzee
Pan troglodytes
XP_001141271
417
45955
S322
P
N
L
P
R
H
I
S
L
T
L
P
A
T
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537843
455
50313
S360
P
N
L
P
R
H
I
S
L
T
L
P
A
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAU4
317
35393
S222
P
N
L
P
R
H
I
S
L
T
L
P
A
T
F
Rat
Rattus norvegicus
Q6P777
271
28734
K177
D
Q
P
K
E
P
S
K
G
S
H
P
E
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508745
413
45132
S318
P
N
L
P
R
H
I
S
L
T
L
P
A
T
F
Chicken
Gallus gallus
Q5ZJX7
267
28044
S173
K
Q
L
S
L
A
D
S
E
Q
Q
A
P
G
K
Frog
Xenopus laevis
Q7ZYJ7
275
29879
A181
Q
P
V
R
R
A
S
A
P
N
P
D
A
G
Q
Zebra Danio
Brachydanio rerio
Q7SXX7
275
29748
N181
P
Q
P
L
K
P
S
N
P
P
E
A
P
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001106142
324
36127
G227
P
Q
I
S
G
S
G
G
K
D
I
E
E
S
D
Nematode Worm
Caenorhab. elegans
NP_501302
277
30361
A183
T
S
N
I
E
S
Q
A
A
G
G
L
Y
P
G
Sea Urchin
Strong. purpuratus
XP_786710
276
31108
Q182
S
S
T
E
L
P
Q
Q
S
G
P
T
Q
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.5
N.A.
68.1
N.A.
96.2
31.3
N.A.
68.2
29.4
28.8
21.6
N.A.
N.A.
25
26.6
31
Protein Similarity:
100
76.5
N.A.
68.7
N.A.
98.1
46
N.A.
72.4
46.7
46.3
34.7
N.A.
N.A.
45.3
47.3
46.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
13.3
13.3
6.6
N.A.
N.A.
6.6
0
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
13.3
26.6
20
N.A.
N.A.
26.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
17
9
0
0
17
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
9
0
0
9
0
9
0
0
9
% D
% Glu:
0
0
0
9
17
0
0
0
9
0
9
9
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% F
% Gly:
0
0
0
0
9
0
9
9
9
17
9
0
0
17
9
% G
% His:
0
0
0
0
0
42
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
42
0
0
0
9
0
0
0
0
% I
% Lys:
9
0
0
9
9
0
0
9
9
0
0
0
0
0
17
% K
% Leu:
0
0
50
9
17
0
0
0
42
0
42
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
42
9
0
0
0
0
9
0
9
0
0
0
0
0
% N
% Pro:
59
9
17
42
0
25
0
0
17
9
17
50
17
17
9
% P
% Gln:
9
34
0
0
0
0
17
9
0
9
9
0
9
0
9
% Q
% Arg:
0
0
0
9
50
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
9
17
0
17
0
17
25
50
9
9
0
0
0
9
0
% S
% Thr:
9
0
9
0
0
0
0
0
0
42
0
9
0
42
9
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _