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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM125B
All Species:
18.18
Human Site:
S295
Identified Species:
36.36
UniProt:
Q9H7P6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7P6
NP_001011703.1
319
35620
S295
I
E
K
E
Y
E
Y
S
F
R
T
E
Q
S
A
Chimpanzee
Pan troglodytes
XP_001141271
417
45955
S393
I
E
K
E
Y
E
Y
S
F
R
T
E
Q
S
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537843
455
50313
S431
I
E
K
E
Y
E
Y
S
F
R
T
E
Q
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAU4
317
35393
S293
I
E
K
E
Y
E
Y
S
F
R
T
E
Q
S
A
Rat
Rattus norvegicus
Q6P777
271
28734
I248
T
I
K
S
L
A
D
I
E
K
E
Y
N
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508745
413
45132
S389
I
E
K
E
Y
D
Y
S
F
R
T
E
Q
S
A
Chicken
Gallus gallus
Q5ZJX7
267
28044
I244
T
V
K
S
L
A
D
I
E
K
E
Y
N
Y
T
Frog
Xenopus laevis
Q7ZYJ7
275
29879
I252
H
I
K
T
L
S
E
I
E
S
E
Y
N
Y
G
Zebra Danio
Brachydanio rerio
Q7SXX7
275
29748
E252
I
K
S
V
Q
D
I
E
N
E
Y
N
Y
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001106142
324
36127
K298
H
S
D
S
S
T
N
K
L
P
V
I
K
N
W
Nematode Worm
Caenorhab. elegans
NP_501302
277
30361
Q254
S
Q
L
P
D
L
S
Q
F
N
D
L
D
R
L
Sea Urchin
Strong. purpuratus
XP_786710
276
31108
N253
Y
K
S
E
M
E
I
N
D
Q
F
Y
Y
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.5
N.A.
68.1
N.A.
96.2
31.3
N.A.
68.2
29.4
28.8
21.6
N.A.
N.A.
25
26.6
31
Protein Similarity:
100
76.5
N.A.
68.7
N.A.
98.1
46
N.A.
72.4
46.7
46.3
34.7
N.A.
N.A.
45.3
47.3
46.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
93.3
6.6
6.6
6.6
N.A.
N.A.
0
6.6
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
13.3
6.6
26.6
N.A.
N.A.
13.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
17
17
0
9
0
9
0
9
9
0
% D
% Glu:
0
42
0
50
0
42
9
9
25
9
25
42
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
50
0
9
0
0
0
17
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
17
0
0
0
0
17
25
0
0
0
9
0
0
0
% I
% Lys:
0
17
67
0
0
0
0
9
0
17
0
0
9
0
0
% K
% Leu:
0
0
9
0
25
9
0
0
9
0
0
9
0
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
9
9
0
9
25
9
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
9
0
0
9
0
0
9
0
9
0
0
42
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
42
0
0
0
9
0
% R
% Ser:
9
9
17
25
9
9
9
42
0
9
0
0
0
42
0
% S
% Thr:
17
0
0
9
0
9
0
0
0
0
42
0
0
9
9
% T
% Val:
0
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
9
0
0
0
42
0
42
0
0
0
9
34
17
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _