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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG2
All Species:
18.18
Human Site:
S417
Identified Species:
50
UniProt:
Q9H7P9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7P9
NP_073746.2
1386
147915
S417
F
F
E
N
H
P
A
S
I
P
A
K
A
K
Q
Chimpanzee
Pan troglodytes
XP_001135904
1385
155562
K422
I
L
E
N
H
A
A
K
I
P
A
K
A
K
Q
Rhesus Macaque
Macaca mulatta
XP_001086919
1534
162840
S564
F
F
E
N
H
P
A
S
I
P
A
K
A
K
Q
Dog
Lupus familis
XP_541623
1488
157673
S477
F
F
E
N
H
P
A
S
I
P
A
K
A
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAU7
1340
143358
S413
F
F
E
N
H
P
A
S
I
P
A
K
A
K
Q
Rat
Rattus norvegicus
NP_001128444
1344
144083
S413
F
F
E
N
H
P
A
S
I
P
A
K
A
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506571
1331
147843
R391
G
W
T
H
H
I
K
R
L
I
L
E
N
H
H
Chicken
Gallus gallus
XP_419671
1405
159118
K407
Q
A
K
S
Q
Q
E
K
R
L
W
I
L
H
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694345
1625
179545
H443
K
R
L
I
V
E
N
H
P
A
S
L
P
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
85.9
73.5
N.A.
70.4
71.7
N.A.
26.3
25
N.A.
28.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.4
87
77.2
N.A.
76.3
77.8
N.A.
39.6
40.2
N.A.
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
6.6
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
33.3
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
12
67
0
0
12
67
0
67
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
67
0
0
12
12
0
0
0
0
12
0
0
0
% E
% Phe:
56
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
12
78
0
0
12
0
0
0
0
0
23
12
% H
% Ile:
12
0
0
12
0
12
0
0
67
12
0
12
0
0
0
% I
% Lys:
12
0
12
0
0
0
12
23
0
0
0
67
0
67
12
% K
% Leu:
0
12
12
0
0
0
0
0
12
12
12
12
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
67
0
0
12
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
56
0
0
12
67
0
0
12
0
0
% P
% Gln:
12
0
0
0
12
12
0
0
0
0
0
0
0
12
67
% Q
% Arg:
0
12
0
0
0
0
0
12
12
0
0
0
0
0
0
% R
% Ser:
0
0
0
12
0
0
0
56
0
0
12
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _