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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST1
All Species:
36.06
Human Site:
S247
Identified Species:
61.03
UniProt:
Q9H7Z6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7Z6
NP_115564.2
458
52403
S247
I
Y
R
K
S
N
I
S
V
Y
E
V
D
G
K
Chimpanzee
Pan troglodytes
XP_523493
344
39260
R136
E
L
A
E
Q
P
E
R
K
I
T
R
N
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536904
458
52471
S247
I
Y
R
K
S
N
I
S
V
Y
E
V
D
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1P2
458
52555
S247
I
Y
R
K
S
N
I
S
V
Y
E
V
D
G
K
Rat
Rattus norvegicus
Q5XI06
458
52614
S247
I
Y
R
K
S
N
I
S
V
Y
E
V
D
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997907
487
55998
S276
I
Y
R
K
N
N
I
S
V
Y
E
V
D
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02193
827
92638
S611
I
Y
R
K
G
N
I
S
I
Y
E
V
N
G
K
Honey Bee
Apis mellifera
XP_625075
455
53401
S244
I
Y
R
K
G
T
L
S
I
W
E
V
D
G
R
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
S241
I
Y
S
H
D
K
L
S
F
F
E
I
D
G
R
Sea Urchin
Strong. purpuratus
XP_790129
425
49269
K217
S
V
Y
E
V
N
G
K
D
H
K
L
Y
C
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001170018
439
50051
R231
P
P
G
D
E
I
Y
R
S
G
T
L
S
M
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
P231
K
C
D
L
K
H
P
P
G
D
E
I
Y
R
S
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
S235
I
Y
R
D
D
Y
V
S
F
F
E
I
D
G
R
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
S293
I
Y
R
D
D
Y
V
S
F
F
E
I
D
G
R
Conservation
Percent
Protein Identity:
100
73.8
N.A.
98.4
N.A.
98.2
97.8
N.A.
N.A.
N.A.
N.A.
79.6
N.A.
34.3
68.3
33.1
65.7
Protein Similarity:
100
74.2
N.A.
98.9
N.A.
98.4
98.4
N.A.
N.A.
N.A.
N.A.
85.2
N.A.
44.7
81
53.7
77.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
80
60
40
6.6
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
93.3
86.6
66.6
40
Percent
Protein Identity:
N.A.
49.3
N.A.
47.6
36
32.4
Protein Similarity:
N.A.
66.3
N.A.
65.9
55.6
52.7
P-Site Identity:
N.A.
0
N.A.
6.6
46.6
46.6
P-Site Similarity:
N.A.
6.6
N.A.
20
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
22
22
0
0
0
8
8
0
0
65
0
0
% D
% Glu:
8
0
0
15
8
0
8
0
0
0
79
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
22
22
0
0
0
0
8
% F
% Gly:
0
0
8
0
15
0
8
0
8
8
0
0
0
72
0
% G
% His:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
72
0
0
0
0
8
43
0
15
8
0
29
0
0
0
% I
% Lys:
8
0
0
50
8
8
0
8
8
0
8
0
0
0
50
% K
% Leu:
0
8
0
8
0
0
15
0
0
0
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
50
0
0
0
0
0
0
15
0
0
% N
% Pro:
8
8
0
0
0
8
8
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
65
0
0
0
0
15
0
0
0
8
0
8
29
% R
% Ser:
8
0
8
0
29
0
0
72
8
0
0
0
8
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
15
0
0
0
0
% T
% Val:
0
8
0
0
8
0
15
0
36
0
0
50
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
72
8
0
0
15
8
0
0
43
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _