Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST1 All Species: 22.42
Human Site: S428 Identified Species: 37.95
UniProt: Q9H7Z6 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7Z6 NP_115564.2 458 52403 S428 L V E E H L K S A Q Y K K P P
Chimpanzee Pan troglodytes XP_523493 344 39260 C316 K G N N A Q P C L P P L L P T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536904 458 52471 S428 L V E E H L K S A Q Y K K P P
Cat Felis silvestris
Mouse Mus musculus Q9D1P2 458 52555 S428 L V E E H L K S A Q Y K K P P
Rat Rattus norvegicus Q5XI06 458 52614 S428 L V E E H L K S A Q Y K K P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997907 487 55998 S457 L V E E H L K S A Q Y K K P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O02193 827 92638 L792 S K T I Q D H L Q L P Q F K Q
Honey Bee Apis mellifera XP_625075 455 53401 S425 L V E E H I K S S Q Y K R P R
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 Q422 V I S D E K R Q V Y E K R I E
Sea Urchin Strong. purpuratus XP_790129 425 49269 P397 K S A Q Y K R P R L T V D T S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001170018 439 50051 L411 I C A D P K V L D R H L K A A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 C411 R K G Q H V I C A D P K V L D
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 L416 I L D R Y N R L K A K K R R T
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 R474 P E K L I K Q R E K S K A K Q
Conservation
Percent
Protein Identity: 100 73.8 N.A. 98.4 N.A. 98.2 97.8 N.A. N.A. N.A. N.A. 79.6 N.A. 34.3 68.3 33.1 65.7
Protein Similarity: 100 74.2 N.A. 98.9 N.A. 98.4 98.4 N.A. N.A. N.A. N.A. 85.2 N.A. 44.7 81 53.7 77.5
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 100 N.A. N.A. N.A. N.A. 100 N.A. 0 73.3 6.6 0
P-Site Similarity: 100 6.6 N.A. 100 N.A. 100 100 N.A. N.A. N.A. N.A. 100 N.A. 6.6 93.3 40 20
Percent
Protein Identity: N.A. 49.3 N.A. 47.6 36 32.4
Protein Similarity: N.A. 66.3 N.A. 65.9 55.6 52.7
P-Site Identity: N.A. 6.6 N.A. 20 6.6 6.6
P-Site Similarity: N.A. 33.3 N.A. 33.3 46.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 0 8 0 0 0 43 8 0 0 8 8 8 % A
% Cys: 0 8 0 0 0 0 0 15 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 15 0 8 0 0 8 8 0 0 8 0 8 % D
% Glu: 0 8 43 43 8 0 0 0 8 0 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 50 0 8 0 0 0 8 0 0 0 0 % H
% Ile: 15 8 0 8 8 8 8 0 0 0 0 0 0 8 0 % I
% Lys: 15 15 8 0 0 29 43 0 8 8 8 72 43 15 0 % K
% Leu: 43 8 0 8 0 36 0 22 8 15 0 15 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 8 0 8 8 0 8 22 0 0 50 36 % P
% Gln: 0 0 0 15 8 8 8 8 8 43 0 8 0 0 15 % Q
% Arg: 8 0 0 8 0 0 22 8 8 8 0 0 22 8 8 % R
% Ser: 8 8 8 0 0 0 0 43 8 0 8 0 0 0 8 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 8 0 0 8 15 % T
% Val: 8 43 0 0 0 8 8 0 8 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 15 0 0 0 0 8 43 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _