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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST1
All Species:
23.64
Human Site:
T139
Identified Species:
40
UniProt:
Q9H7Z6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7Z6
NP_115564.2
458
52403
T139
E
Q
P
E
R
K
I
T
R
N
Q
K
R
K
H
Chimpanzee
Pan troglodytes
XP_523493
344
39260
E32
P
G
E
N
A
A
A
E
G
T
A
P
S
P
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536904
458
52471
T139
E
Q
P
E
R
K
I
T
R
N
Q
K
R
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1P2
458
52555
T139
E
Q
P
E
R
K
I
T
R
N
Q
K
R
K
H
Rat
Rattus norvegicus
Q5XI06
458
52614
T139
E
Q
P
E
R
K
I
T
R
N
Q
K
R
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997907
487
55998
I167
V
D
Q
P
E
R
K
I
T
R
N
Q
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02193
827
92638
T503
D
Y
S
D
R
K
M
T
R
Y
Q
K
R
R
Y
Honey Bee
Apis mellifera
XP_625075
455
53401
T136
D
S
S
D
R
K
I
T
R
N
Q
K
R
R
H
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
E134
P
M
D
D
L
K
A
E
S
V
D
P
L
Q
A
Sea Urchin
Strong. purpuratus
XP_790129
425
49269
N113
K
R
K
H
D
E
I
N
H
V
Q
K
S
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001170018
439
50051
T127
E
K
V
E
D
K
A
T
S
L
K
M
T
R
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
D126
D
S
V
E
C
A
V
D
E
K
V
E
D
K
V
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
N128
T
D
V
M
D
L
D
N
L
N
V
Q
G
I
K
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
D169
A
S
L
E
V
G
G
D
K
G
V
K
R
K
A
Conservation
Percent
Protein Identity:
100
73.8
N.A.
98.4
N.A.
98.2
97.8
N.A.
N.A.
N.A.
N.A.
79.6
N.A.
34.3
68.3
33.1
65.7
Protein Similarity:
100
74.2
N.A.
98.9
N.A.
98.4
98.4
N.A.
N.A.
N.A.
N.A.
85.2
N.A.
44.7
81
53.7
77.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
0
N.A.
46.6
66.6
6.6
20
P-Site Similarity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
80
86.6
20
40
Percent
Protein Identity:
N.A.
49.3
N.A.
47.6
36
32.4
Protein Similarity:
N.A.
66.3
N.A.
65.9
55.6
52.7
P-Site Identity:
N.A.
33.3
N.A.
13.3
6.6
26.6
P-Site Similarity:
N.A.
53.3
N.A.
33.3
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
15
22
0
0
0
8
0
0
0
22
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
15
8
22
22
0
8
15
0
0
8
0
8
0
0
% D
% Glu:
36
0
8
50
8
8
0
15
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
0
8
8
0
8
8
0
0
8
0
8
% G
% His:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
43
% H
% Ile:
0
0
0
0
0
0
43
8
0
0
0
0
0
8
0
% I
% Lys:
8
8
8
0
0
58
8
0
8
8
8
58
8
43
15
% K
% Leu:
0
0
8
0
8
8
0
0
8
8
0
0
8
0
0
% L
% Met:
0
8
0
8
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
15
0
43
8
0
0
0
0
% N
% Pro:
15
0
29
8
0
0
0
0
0
0
0
15
0
8
0
% P
% Gln:
0
29
8
0
0
0
0
0
0
0
50
15
0
8
0
% Q
% Arg:
0
8
0
0
43
8
0
0
43
8
0
0
50
29
0
% R
% Ser:
0
22
15
0
0
0
0
0
15
0
0
0
15
0
0
% S
% Thr:
8
0
0
0
0
0
0
50
8
8
0
0
8
0
0
% T
% Val:
8
0
22
0
8
0
8
0
0
15
22
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _