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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST1 All Species: 13.64
Human Site: T45 Identified Species: 23.08
UniProt: Q9H7Z6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7Z6 NP_115564.2 458 52403 T45 P G R V S P P T P A R G E P E
Chimpanzee Pan troglodytes XP_523493 344 39260
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536904 458 52471 T45 P G R V S P P T P A R G E P E
Cat Felis silvestris
Mouse Mus musculus Q9D1P2 458 52555 T45 P G R V S P P T P A R G E P E
Rat Rattus norvegicus Q5XI06 458 52614 T45 P G R V S P P T P A R G E P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997907 487 55998 L73 R S A D G V S L G G G R E Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O02193 827 92638 D367 E T V I T T G D P L M Q K I D
Honey Bee Apis mellifera XP_625075 455 53401 D39 N G G K G S G D D A D S L E E
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 M40 G C R L L V M M A S Q E E E R
Sea Urchin Strong. purpuratus XP_790129 425 49269 N22 K A Q E N N M N S S L K D T D
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001170018 439 50051 L37 G G G V E R R L R S S A A P A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 P36 D G S H P P P P P L T P D Q A
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 L37 Q K N D E E R L A E I L S I N
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 A75 L D E W V P A A R I D F E Q D
Conservation
Percent
Protein Identity: 100 73.8 N.A. 98.4 N.A. 98.2 97.8 N.A. N.A. N.A. N.A. 79.6 N.A. 34.3 68.3 33.1 65.7
Protein Similarity: 100 74.2 N.A. 98.9 N.A. 98.4 98.4 N.A. N.A. N.A. N.A. 85.2 N.A. 44.7 81 53.7 77.5
P-Site Identity: 100 0 N.A. 100 N.A. 100 100 N.A. N.A. N.A. N.A. 13.3 N.A. 6.6 20 13.3 0
P-Site Similarity: 100 0 N.A. 100 N.A. 100 100 N.A. N.A. N.A. N.A. 13.3 N.A. 33.3 20 33.3 33.3
Percent
Protein Identity: N.A. 49.3 N.A. 47.6 36 32.4
Protein Similarity: N.A. 66.3 N.A. 65.9 55.6 52.7
P-Site Identity: N.A. 20 N.A. 26.6 0 13.3
P-Site Similarity: N.A. 26.6 N.A. 33.3 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 8 8 15 36 0 8 8 0 15 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 15 0 0 0 15 8 0 15 0 15 0 22 % D
% Glu: 8 0 8 8 15 8 0 0 0 8 0 8 50 15 43 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 15 50 15 0 15 0 15 0 8 8 8 29 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 8 8 0 0 15 0 % I
% Lys: 8 8 0 8 0 0 0 0 0 0 0 8 8 0 0 % K
% Leu: 8 0 0 8 8 0 0 22 0 15 8 8 8 0 0 % L
% Met: 0 0 0 0 0 0 15 8 0 0 8 0 0 0 0 % M
% Asn: 8 0 8 0 8 8 0 8 0 0 0 0 0 0 8 % N
% Pro: 29 0 0 0 8 43 36 8 43 0 0 8 0 36 0 % P
% Gln: 8 0 8 0 0 0 0 0 0 0 8 8 0 22 0 % Q
% Arg: 8 0 36 0 0 8 15 0 15 0 29 8 0 0 8 % R
% Ser: 0 8 8 0 29 8 8 0 8 22 8 8 8 0 0 % S
% Thr: 0 8 0 0 8 8 0 29 0 0 8 0 0 8 0 % T
% Val: 0 0 8 36 8 15 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _