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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGES2
All Species:
28.79
Human Site:
S247
Identified Species:
48.72
UniProt:
Q9H7Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7Z7
NP_079348.1
377
41943
S247
D
W
L
V
H
L
I
S
P
N
V
Y
R
T
P
Chimpanzee
Pan troglodytes
XP_001153561
186
21319
K78
D
Y
I
V
R
E
G
K
F
G
A
V
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001091842
377
41946
S247
D
W
L
V
H
L
I
S
P
N
V
Y
R
T
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWM0
384
43289
S246
D
W
L
V
H
L
I
S
P
N
V
Y
R
T
P
Rat
Rattus norvegicus
NP_001101302
384
43433
S246
D
W
L
V
H
L
I
S
P
N
V
Y
R
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519082
201
23462
T93
K
S
L
E
E
I
I
T
Y
Y
P
P
M
K
T
Chicken
Gallus gallus
XP_415498
350
39599
S222
D
W
L
V
H
L
I
S
P
N
V
Y
R
T
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZUC7
377
42774
S250
D
W
L
V
H
L
I
S
P
N
V
Y
R
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524116
417
47091
S270
S
H
L
V
H
L
I
S
P
N
C
Y
Q
T
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501913
347
40274
A235
D
W
H
R
T
F
P
A
W
E
R
V
L
A
V
Sea Urchin
Strong. purpuratus
XP_789825
398
45229
P269
N
V
L
V
H
N
L
P
P
N
I
Y
R
S
P
Poplar Tree
Populus trichocarpa
XP_002317870
327
36570
S217
E
S
F
D
Y
I
T
S
N
G
N
F
S
F
T
Maize
Zea mays
NP_001130206
322
35753
F214
A
K
H
G
N
F
S
F
T
E
R
F
A
V
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199030
315
35531
G207
F
E
Y
I
T
T
H
G
N
F
S
F
T
E
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.3
97
N.A.
N.A.
82.2
82.2
N.A.
38.9
66
N.A.
58.6
N.A.
35
N.A.
38.4
40.9
Protein Similarity:
100
49.3
97.3
N.A.
N.A.
87.2
87.5
N.A.
45
74.2
N.A.
74.5
N.A.
51.3
N.A.
56.5
57.2
P-Site Identity:
100
13.3
100
N.A.
N.A.
100
100
N.A.
13.3
100
N.A.
100
N.A.
66.6
N.A.
13.3
53.3
P-Site Similarity:
100
26.6
100
N.A.
N.A.
100
100
N.A.
26.6
100
N.A.
100
N.A.
73.3
N.A.
20
80
Percent
Protein Identity:
37.6
39.7
N.A.
37.6
N.A.
N.A.
Protein Similarity:
53.8
54.1
N.A.
54.1
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
8
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
58
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
8
8
0
0
0
15
0
0
8
8
0
% E
% Phe:
8
0
8
0
0
15
0
8
8
8
0
22
0
8
0
% F
% Gly:
0
0
0
8
0
0
8
8
0
15
0
0
0
8
0
% G
% His:
0
8
15
0
58
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
15
58
0
0
0
8
0
0
0
0
% I
% Lys:
8
8
0
0
0
0
0
8
0
0
0
0
0
8
8
% K
% Leu:
0
0
65
0
0
50
8
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
8
0
0
0
8
8
0
0
15
58
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
58
0
8
8
0
0
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
15
0
50
0
8
% R
% Ser:
8
15
0
0
0
0
8
58
0
0
8
0
8
8
0
% S
% Thr:
0
0
0
0
15
8
8
8
8
0
0
0
8
50
15
% T
% Val:
0
8
0
65
0
0
0
0
0
0
43
15
0
8
8
% V
% Trp:
0
50
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
8
0
0
0
8
8
0
58
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _