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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTGES2 All Species: 24.55
Human Site: S260 Identified Species: 41.54
UniProt: Q9H7Z7 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7Z7 NP_079348.1 377 41943 S260 T P T E A L A S F D Y I V R E
Chimpanzee Pan troglodytes XP_001153561 186 21319 G91 G A V A K Y M G A A A M Y L I
Rhesus Macaque Macaca mulatta XP_001091842 377 41946 S260 T P T E A L A S F D Y I V R E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BWM0 384 43289 S259 T P A E A L A S F D Y I V R E
Rat Rattus norvegicus NP_001101302 384 43433 S259 T P A E A L A S F D Y I V R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519082 201 23462 K106 K T V N D R G K E V T E Y G N
Chicken Gallus gallus XP_415498 350 39599 S235 T P K E A L A S F D Y I V R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7ZUC7 377 42774 S263 T P T E A L A S F D Y I V R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524116 417 47091 T283 T M G E S L E T F E W F S Q A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501913 347 40274 A248 A V Y V G A A A M F L L S K T
Sea Urchin Strong. purpuratus XP_789825 398 45229 A282 S P S E A L Q A F S Y I S S L
Poplar Tree Populus trichocarpa XP_002317870 327 36570 K230 F T E K I T V K Y A G A A A M
Maize Zea mays NP_001130206 322 35753 A227 V K Y A G A A A M Y M V S K K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199030 315 35531 A220 E R L V A K Y A G A T A M Y F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.3 97 N.A. N.A. 82.2 82.2 N.A. 38.9 66 N.A. 58.6 N.A. 35 N.A. 38.4 40.9
Protein Similarity: 100 49.3 97.3 N.A. N.A. 87.2 87.5 N.A. 45 74.2 N.A. 74.5 N.A. 51.3 N.A. 56.5 57.2
P-Site Identity: 100 0 100 N.A. N.A. 93.3 93.3 N.A. 0 93.3 N.A. 100 N.A. 26.6 N.A. 6.6 46.6
P-Site Similarity: 100 6.6 100 N.A. N.A. 93.3 93.3 N.A. 0 93.3 N.A. 100 N.A. 60 N.A. 26.6 66.6
Percent
Protein Identity: 37.6 39.7 N.A. 37.6 N.A. N.A.
Protein Similarity: 53.8 54.1 N.A. 54.1 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 33.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 15 58 15 58 29 8 22 8 15 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 43 0 0 0 0 0 % D
% Glu: 8 0 8 58 0 0 8 0 8 8 0 8 0 0 43 % E
% Phe: 8 0 0 0 0 0 0 0 58 8 0 8 0 0 8 % F
% Gly: 8 0 8 0 15 0 8 8 8 0 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 50 0 0 8 % I
% Lys: 8 8 8 8 8 8 0 15 0 0 0 0 0 15 8 % K
% Leu: 0 0 8 0 0 58 0 0 0 0 8 8 0 8 8 % L
% Met: 0 8 0 0 0 0 8 0 15 0 8 8 8 0 8 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 8 0 0 0 8 0 0 0 0 0 0 0 43 0 % R
% Ser: 8 0 8 0 8 0 0 43 0 8 0 0 29 8 0 % S
% Thr: 50 15 22 0 0 8 0 8 0 0 15 0 0 0 8 % T
% Val: 8 8 15 15 0 0 8 0 0 8 0 8 43 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 15 0 0 8 8 0 8 8 50 0 15 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _