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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTGES2 All Species: 26.67
Human Site: Y263 Identified Species: 45.13
UniProt: Q9H7Z7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H7Z7 NP_079348.1 377 41943 Y263 E A L A S F D Y I V R E G K F
Chimpanzee Pan troglodytes XP_001153561 186 21319 A94 A K Y M G A A A M Y L I S K R
Rhesus Macaque Macaca mulatta XP_001091842 377 41946 Y263 E A L A S F D Y I V R E G K F
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BWM0 384 43289 Y262 E A L A S F D Y I V R E G K F
Rat Rattus norvegicus NP_001101302 384 43433 Y262 E A L A S F D Y I V R E G K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519082 201 23462 T109 N D R G K E V T E Y G N K Y W
Chicken Gallus gallus XP_415498 350 39599 Y238 E A L A S F D Y I V R E G K F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7ZUC7 377 42774 Y266 E A L A S F D Y I V R E G K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524116 417 47091 W286 E S L E T F E W F S Q A G E W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501913 347 40274 L251 V G A A A M F L L S K T L K K
Sea Urchin Strong. purpuratus XP_789825 398 45229 Y285 E A L Q A F S Y I S S L G N F
Poplar Tree Populus trichocarpa XP_002317870 327 36570 G233 K I T V K Y A G A A A M Y F V
Maize Zea mays NP_001130206 322 35753 M230 A G A A A M Y M V S K K L K K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199030 315 35531 T223 V A K Y A G A T A M Y F V S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.3 97 N.A. N.A. 82.2 82.2 N.A. 38.9 66 N.A. 58.6 N.A. 35 N.A. 38.4 40.9
Protein Similarity: 100 49.3 97.3 N.A. N.A. 87.2 87.5 N.A. 45 74.2 N.A. 74.5 N.A. 51.3 N.A. 56.5 57.2
P-Site Identity: 100 6.6 100 N.A. N.A. 100 100 N.A. 0 100 N.A. 100 N.A. 26.6 N.A. 13.3 53.3
P-Site Similarity: 100 13.3 100 N.A. N.A. 100 100 N.A. 6.6 100 N.A. 100 N.A. 73.3 N.A. 33.3 60
Percent
Protein Identity: 37.6 39.7 N.A. 37.6 N.A. N.A.
Protein Similarity: 53.8 54.1 N.A. 54.1 N.A. N.A.
P-Site Identity: 0 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 40 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 58 15 58 29 8 22 8 15 8 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 43 0 0 0 0 0 0 0 0 % D
% Glu: 58 0 0 8 0 8 8 0 8 0 0 43 0 8 0 % E
% Phe: 0 0 0 0 0 58 8 0 8 0 0 8 0 8 50 % F
% Gly: 0 15 0 8 8 8 0 8 0 0 8 0 58 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 50 0 0 8 0 0 0 % I
% Lys: 8 8 8 0 15 0 0 0 0 0 15 8 8 65 22 % K
% Leu: 0 0 58 0 0 0 0 8 8 0 8 8 15 0 0 % L
% Met: 0 0 0 8 0 15 0 8 8 8 0 8 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 43 0 0 0 8 % R
% Ser: 0 8 0 0 43 0 8 0 0 29 8 0 8 8 0 % S
% Thr: 0 0 8 0 8 0 0 15 0 0 0 8 0 0 0 % T
% Val: 15 0 0 8 0 0 8 0 8 43 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 15 % W
% Tyr: 0 0 8 8 0 8 8 50 0 15 8 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _