KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLE6
All Species:
12.73
Human Site:
S118
Identified Species:
23.33
UniProt:
Q9H808
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H808
NP_001137458.1
449
49827
S118
Q
E
P
P
G
R
A
S
R
F
L
Q
S
I
S
Chimpanzee
Pan troglodytes
XP_512978
572
63399
S241
Q
E
P
P
G
R
A
S
R
F
L
Q
S
I
S
Rhesus Macaque
Macaca mulatta
XP_001102405
653
69655
T220
P
T
P
G
S
N
S
T
P
G
L
R
P
V
P
Dog
Lupus familis
XP_542184
560
61529
C229
Q
E
P
A
G
R
A
C
P
F
L
K
P
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVB3
581
65097
D248
Q
E
S
S
G
R
A
D
K
F
L
K
P
L
S
Rat
Rattus norvegicus
Q07141
748
81316
T315
P
T
P
G
S
N
S
T
P
G
L
R
P
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511869
767
82903
T334
P
T
P
G
S
N
S
T
P
G
L
R
P
V
P
Chicken
Gallus gallus
NP_989568
773
83801
T340
P
T
P
G
S
N
S
T
P
G
L
R
P
V
P
Frog
Xenopus laevis
O42469
767
82956
A345
P
G
P
S
G
T
S
A
S
Q
F
R
S
I
A
Zebra Danio
Brachydanio rerio
O13166
761
82441
A297
P
R
R
P
A
S
V
A
S
S
G
S
T
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16371
730
80213
A332
R
T
P
T
P
N
A
A
A
P
A
P
G
V
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02482
612
65598
S254
P
N
L
L
R
Q
A
S
A
A
G
G
F
N
F
Sea Urchin
Strong. purpuratus
XP_792326
737
80564
E321
S
P
A
P
P
K
S
E
T
P
T
S
S
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.2
25.5
53.7
N.A.
41.4
24.4
N.A.
23.3
22.7
22.9
23.5
N.A.
21.7
N.A.
23.8
23.2
Protein Similarity:
100
77.9
40.5
62.1
N.A.
52.1
37.4
N.A.
35.9
35.8
36.9
37.3
N.A.
36.5
N.A.
40.6
37.1
P-Site Identity:
100
100
13.3
60
N.A.
53.3
13.3
N.A.
13.3
13.3
26.6
13.3
N.A.
13.3
N.A.
13.3
13.3
P-Site Similarity:
100
100
40
66.6
N.A.
73.3
40
N.A.
40
40
53.3
26.6
N.A.
40
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
47
24
16
8
8
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
31
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
31
8
0
8
0
8
% F
% Gly:
0
8
0
31
39
0
0
0
0
31
16
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% I
% Lys:
0
0
0
0
0
8
0
0
8
0
0
16
0
0
0
% K
% Leu:
0
0
8
8
0
0
0
0
0
0
62
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
39
0
0
0
0
0
0
0
8
8
% N
% Pro:
54
8
70
31
16
0
0
0
39
16
0
8
47
8
31
% P
% Gln:
31
0
0
0
0
8
0
0
0
8
0
16
0
0
0
% Q
% Arg:
8
8
8
0
8
31
0
0
16
0
0
39
0
0
0
% R
% Ser:
8
0
8
16
31
8
47
24
16
8
0
16
31
0
31
% S
% Thr:
0
39
0
8
0
8
0
31
8
0
8
0
8
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _