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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLE6
All Species:
9.39
Human Site:
S123
Identified Species:
17.22
UniProt:
Q9H808
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H808
NP_001137458.1
449
49827
S123
R
A
S
R
F
L
Q
S
I
S
W
D
P
E
D
Chimpanzee
Pan troglodytes
XP_512978
572
63399
S246
R
A
S
R
F
L
Q
S
I
S
W
D
P
E
D
Rhesus Macaque
Macaca mulatta
XP_001102405
653
69655
P225
N
S
T
P
G
L
R
P
V
P
G
K
P
P
G
Dog
Lupus familis
XP_542184
560
61529
P234
R
A
C
P
F
L
K
P
I
L
W
D
P
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVB3
581
65097
P253
R
A
D
K
F
L
K
P
L
S
W
G
S
E
V
Rat
Rattus norvegicus
Q07141
748
81316
P320
N
S
T
P
G
L
R
P
V
P
G
K
P
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511869
767
82903
P339
N
S
T
P
G
L
R
P
V
P
G
K
P
P
G
Chicken
Gallus gallus
NP_989568
773
83801
P345
N
S
T
P
G
L
R
P
V
P
G
K
P
P
G
Frog
Xenopus laevis
O42469
767
82956
S350
T
S
A
S
Q
F
R
S
I
A
T
K
P
A
I
Zebra Danio
Brachydanio rerio
O13166
761
82441
T302
S
V
A
S
S
G
S
T
P
S
S
K
T
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16371
730
80213
G337
N
A
A
A
P
A
P
G
V
N
P
K
Q
M
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02482
612
65598
F259
Q
A
S
A
A
G
G
F
N
F
L
N
D
P
H
Sea Urchin
Strong. purpuratus
XP_792326
737
80564
S326
K
S
E
T
P
T
S
S
G
A
A
T
P
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.2
25.5
53.7
N.A.
41.4
24.4
N.A.
23.3
22.7
22.9
23.5
N.A.
21.7
N.A.
23.8
23.2
Protein Similarity:
100
77.9
40.5
62.1
N.A.
52.1
37.4
N.A.
35.9
35.8
36.9
37.3
N.A.
36.5
N.A.
40.6
37.1
P-Site Identity:
100
100
13.3
66.6
N.A.
46.6
13.3
N.A.
13.3
13.3
20
6.6
N.A.
6.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
40
73.3
N.A.
66.6
40
N.A.
40
40
46.6
26.6
N.A.
26.6
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
24
16
8
8
0
0
0
16
8
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
24
8
0
24
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
31
0
% E
% Phe:
0
0
0
0
31
8
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
31
16
8
8
8
0
31
8
0
8
31
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
8
% I
% Lys:
8
0
0
8
0
0
16
0
0
0
0
54
0
8
0
% K
% Leu:
0
0
0
0
0
62
0
0
8
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
39
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% N
% Pro:
0
0
0
39
16
0
8
47
8
31
8
0
70
39
8
% P
% Gln:
8
0
0
0
8
0
16
0
0
0
0
0
8
0
0
% Q
% Arg:
31
0
0
16
0
0
39
0
0
0
0
0
0
0
0
% R
% Ser:
8
47
24
16
8
0
16
31
0
31
8
0
8
0
8
% S
% Thr:
8
0
31
8
0
8
0
8
0
0
8
8
8
0
0
% T
% Val:
0
8
0
0
0
0
0
0
39
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _