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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLE6
All Species:
7.88
Human Site:
S190
Identified Species:
14.44
UniProt:
Q9H808
Number Species:
12
Phosphosite Substitution
Charge Score:
0.75
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H808
NP_001137458.1
449
49827
S190
R
R
G
I
K
V
W
S
L
T
G
Q
V
A
E
Chimpanzee
Pan troglodytes
XP_512978
572
63399
S313
R
R
G
I
K
V
W
S
L
T
G
Q
V
A
E
Rhesus Macaque
Macaca mulatta
XP_001102405
653
69655
D394
K
G
C
V
K
V
W
D
I
S
H
P
G
N
K
Dog
Lupus familis
XP_542184
560
61529
S301
R
G
G
V
K
V
W
S
L
V
G
Q
G
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVB3
581
65097
N320
Q
S
G
I
K
V
W
N
L
V
N
Q
V
A
E
Rat
Rattus norvegicus
Q07141
748
81316
D489
K
G
C
V
K
V
W
D
I
T
D
P
G
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511869
767
82903
D508
K
G
C
V
K
V
W
D
I
S
Q
P
G
N
K
Chicken
Gallus gallus
NP_989568
773
83801
D514
K
G
C
V
K
V
W
D
I
S
H
P
G
N
K
Frog
Xenopus laevis
O42469
767
82956
D508
K
G
C
V
K
V
W
D
V
G
Q
P
G
T
K
Zebra Danio
Brachydanio rerio
O13166
761
82441
D502
K
G
C
V
K
I
W
D
I
S
Q
P
G
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16371
730
80213
D471
K
G
C
V
K
V
W
D
I
S
Q
P
G
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02482
612
65598
D349
K
G
C
V
K
I
W
D
V
K
E
S
D
I
S
Sea Urchin
Strong. purpuratus
XP_792326
737
80564
D478
K
G
C
V
K
V
W
D
I
S
Q
S
G
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.2
25.5
53.7
N.A.
41.4
24.4
N.A.
23.3
22.7
22.9
23.5
N.A.
21.7
N.A.
23.8
23.2
Protein Similarity:
100
77.9
40.5
62.1
N.A.
52.1
37.4
N.A.
35.9
35.8
36.9
37.3
N.A.
36.5
N.A.
40.6
37.1
P-Site Identity:
100
100
20
66.6
N.A.
66.6
26.6
N.A.
20
20
20
13.3
N.A.
20
N.A.
13.3
20
P-Site Similarity:
100
100
53.3
73.3
N.A.
80
53.3
N.A.
53.3
53.3
46.6
60
N.A.
53.3
N.A.
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% A
% Cys:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
70
0
0
8
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
31
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
77
31
0
0
0
0
0
0
8
24
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% H
% Ile:
0
0
0
24
0
16
0
0
54
0
0
0
0
8
0
% I
% Lys:
70
0
0
0
100
0
0
0
0
8
0
0
0
0
54
% K
% Leu:
0
0
0
0
0
0
0
0
31
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
47
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
39
31
0
0
0
% Q
% Arg:
24
16
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
0
0
0
0
0
24
0
47
0
16
0
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
24
0
0
0
8
0
% T
% Val:
0
0
0
77
0
85
0
0
16
16
0
0
24
0
0
% V
% Trp:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _