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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLE6
All Species:
7.27
Human Site:
S67
Identified Species:
13.33
UniProt:
Q9H808
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H808
NP_001137458.1
449
49827
S67
A
P
G
L
G
Q
E
S
K
A
P
G
S
C
D
Chimpanzee
Pan troglodytes
XP_512978
572
63399
S190
A
P
G
L
G
Q
E
S
K
A
P
A
S
C
D
Rhesus Macaque
Macaca mulatta
XP_001102405
653
69655
A169
T
R
L
L
K
K
D
A
P
I
S
P
A
S
I
Dog
Lupus familis
XP_542184
560
61529
L178
P
H
P
P
G
L
E
L
R
T
E
D
P
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVB3
581
65097
D197
S
K
D
S
G
L
C
D
F
K
P
E
P
Q
P
Rat
Rattus norvegicus
Q07141
748
81316
A264
T
R
L
L
K
K
D
A
P
I
S
P
A
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511869
767
82903
A283
T
R
L
L
K
K
D
A
P
M
S
P
A
S
I
Chicken
Gallus gallus
NP_989568
773
83801
A289
T
R
L
L
K
K
D
A
P
I
S
P
A
S
I
Frog
Xenopus laevis
O42469
767
82956
P294
K
D
P
P
P
A
S
P
N
S
M
T
S
S
S
Zebra Danio
Brachydanio rerio
O13166
761
82441
S246
D
S
M
S
R
Y
D
S
D
G
D
K
S
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16371
730
80213
L281
E
S
L
N
G
E
R
L
E
K
P
S
S
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02482
612
65598
S203
A
N
K
N
G
R
D
S
T
N
S
V
A
S
S
Sea Urchin
Strong. purpuratus
XP_792326
737
80564
E270
Q
M
S
P
R
E
R
E
R
E
R
E
N
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.2
25.5
53.7
N.A.
41.4
24.4
N.A.
23.3
22.7
22.9
23.5
N.A.
21.7
N.A.
23.8
23.2
Protein Similarity:
100
77.9
40.5
62.1
N.A.
52.1
37.4
N.A.
35.9
35.8
36.9
37.3
N.A.
36.5
N.A.
40.6
37.1
P-Site Identity:
100
93.3
6.6
13.3
N.A.
13.3
6.6
N.A.
6.6
6.6
6.6
20
N.A.
20
N.A.
20
0
P-Site Similarity:
100
93.3
33.3
20
N.A.
20
33.3
N.A.
33.3
33.3
13.3
26.6
N.A.
33.3
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
0
0
8
0
31
0
16
0
8
39
8
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
16
0
% C
% Asp:
8
8
8
0
0
0
47
8
8
0
8
8
0
8
24
% D
% Glu:
8
0
0
0
0
16
24
8
8
8
8
16
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
16
0
47
0
0
0
0
8
0
8
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
24
% I
% Lys:
8
8
8
0
31
31
0
0
16
16
0
8
0
0
0
% K
% Leu:
0
0
39
47
0
16
0
16
0
0
0
0
0
8
0
% L
% Met:
0
8
8
0
0
0
0
0
0
8
8
0
0
0
8
% M
% Asn:
0
8
0
16
0
0
0
0
8
8
0
0
8
0
0
% N
% Pro:
8
16
16
24
8
0
0
8
31
0
31
31
16
0
8
% P
% Gln:
8
0
0
0
0
16
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
31
0
0
16
8
16
0
16
0
8
0
0
0
0
% R
% Ser:
8
16
8
16
0
0
8
31
0
8
39
8
39
54
16
% S
% Thr:
31
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _