Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLE6 All Species: 12.73
Human Site: S94 Identified Species: 23.33
UniProt: Q9H808 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H808 NP_001137458.1 449 49827 S94 P R P P E A S S S P P E G S Q
Chimpanzee Pan troglodytes XP_512978 572 63399 S217 P R P P E A S S S P P E G S Q
Rhesus Macaque Macaca mulatta XP_001102405 653 69655 S196 E L S L N E K S T T P V S K S
Dog Lupus familis XP_542184 560 61529 G205 S P E G S Q E G S A E P G T G
Cat Felis silvestris
Mouse Mus musculus Q9WVB3 581 65097 A224 F L I K S P S A L L D Y Y Q E
Rat Rattus norvegicus Q07141 748 81316 S291 E L S L N E K S T T P V S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511869 767 82903 S310 E L S L N E K S T T P V S K S
Chicken Gallus gallus NP_989568 773 83801 S316 E L S L N E K S T T P V S K S
Frog Xenopus laevis O42469 767 82956 T321 Q Q V E K A G T P G L K S S T
Zebra Danio Brachydanio rerio O13166 761 82441 S273 P R G S P A H S P P E N G I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16371 730 80213 S308 S S S R S T P S L K T K D M E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02482 612 65598 L230 A R Q Q Q Q P L A G L Q G L E
Sea Urchin Strong. purpuratus XP_792326 737 80564 A297 P N S I A S S A S S P Q S K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.2 25.5 53.7 N.A. 41.4 24.4 N.A. 23.3 22.7 22.9 23.5 N.A. 21.7 N.A. 23.8 23.2
Protein Similarity: 100 77.9 40.5 62.1 N.A. 52.1 37.4 N.A. 35.9 35.8 36.9 37.3 N.A. 36.5 N.A. 40.6 37.1
P-Site Identity: 100 100 13.3 13.3 N.A. 6.6 13.3 N.A. 13.3 13.3 13.3 40 N.A. 6.6 N.A. 13.3 26.6
P-Site Similarity: 100 100 20 20 N.A. 20 20 N.A. 20 20 40 40 N.A. 20 N.A. 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 31 0 16 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 8 % D
% Glu: 31 0 8 8 16 31 8 0 0 0 16 16 0 0 24 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 0 8 8 0 16 0 0 39 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 8 8 0 31 0 0 8 0 16 0 39 0 % K
% Leu: 0 39 0 31 0 0 0 8 16 8 16 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 8 0 0 31 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 31 8 16 16 8 8 16 0 16 24 54 8 0 0 8 % P
% Gln: 8 8 8 8 8 16 0 0 0 0 0 16 0 8 16 % Q
% Arg: 0 31 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 8 47 8 24 8 31 62 31 8 0 0 47 24 31 % S
% Thr: 0 0 0 0 0 8 0 8 31 31 8 0 0 8 8 % T
% Val: 0 0 8 0 0 0 0 0 0 0 0 31 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _