KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLE6
All Species:
23.64
Human Site:
Y309
Identified Species:
43.33
UniProt:
Q9H808
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H808
NP_001137458.1
449
49827
Y309
K
S
I
V
V
K
G
Y
N
I
W
T
G
G
P
Chimpanzee
Pan troglodytes
XP_512978
572
63399
Y432
K
S
I
V
V
K
G
Y
N
I
W
T
G
G
P
Rhesus Macaque
Macaca mulatta
XP_001102405
653
69655
T512
I
D
I
S
N
D
G
T
K
L
W
T
G
G
L
Dog
Lupus familis
XP_542184
560
61529
Q420
K
S
I
A
V
K
E
Q
N
I
W
T
G
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVB3
581
65097
D440
R
N
L
V
V
K
D
D
N
I
W
T
G
G
L
Rat
Rattus norvegicus
Q07141
748
81316
T607
I
D
I
S
N
D
G
T
K
L
W
T
G
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511869
767
82903
T626
I
D
I
S
N
D
G
T
K
L
W
T
G
G
L
Chicken
Gallus gallus
NP_989568
773
83801
T632
I
D
I
S
N
D
G
T
K
L
W
T
G
G
L
Frog
Xenopus laevis
O42469
767
82956
T626
I
D
I
S
H
D
G
T
K
L
W
T
G
G
L
Zebra Danio
Brachydanio rerio
O13166
761
82441
T620
I
D
I
S
H
D
G
T
K
L
W
T
G
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16371
730
80213
S589
I
D
I
S
P
D
G
S
R
L
W
T
G
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02482
612
65598
T471
L
D
L
S
K
D
G
T
K
L
W
S
G
G
L
Sea Urchin
Strong. purpuratus
XP_792326
737
80564
S596
I
D
I
S
P
D
G
S
K
L
W
T
G
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.2
25.5
53.7
N.A.
41.4
24.4
N.A.
23.3
22.7
22.9
23.5
N.A.
21.7
N.A.
23.8
23.2
Protein Similarity:
100
77.9
40.5
62.1
N.A.
52.1
37.4
N.A.
35.9
35.8
36.9
37.3
N.A.
36.5
N.A.
40.6
37.1
P-Site Identity:
100
100
40
73.3
N.A.
60
40
N.A.
40
40
40
40
N.A.
40
N.A.
26.6
40
P-Site Similarity:
100
100
46.6
73.3
N.A.
80
46.6
N.A.
46.6
46.6
46.6
46.6
N.A.
46.6
N.A.
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
0
0
70
8
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
85
0
0
0
0
0
100
100
0
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
62
0
85
0
0
0
0
0
0
31
0
0
0
0
0
% I
% Lys:
24
0
0
0
8
31
0
0
62
0
0
0
0
0
0
% K
% Leu:
8
0
16
0
0
0
0
0
0
70
0
0
0
0
85
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
31
0
0
0
31
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
16
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
24
0
70
0
0
0
16
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
54
0
0
0
93
0
0
0
% T
% Val:
0
0
0
24
31
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _