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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1B All Species: 12.12
Human Site: S370 Identified Species: 24.24
UniProt: Q9H816 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H816 NP_073747.1 532 60002 S370 Q S Q A D R D S K K A K K E K
Chimpanzee Pan troglodytes XP_524804 532 59965 S370 Q S Q A D R D S K K A K K E K
Rhesus Macaque Macaca mulatta XP_001110949 532 60020 S370 Q S Q A D R D S K K T Q K E K
Dog Lupus familis XP_848274 530 59628 D369 T A D Q S Q A D G D S K K A K
Cat Felis silvestris
Mouse Mus musculus Q8C7W7 541 61051 S371 Q V K V D R D S K K H K K E N
Rat Rattus norvegicus Q5XIX3 698 78171 C433 E L G Q S P G C C K A E S M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506464 563 63126 P373 P S L E S K E P Q G S Q A W E
Chicken Gallus gallus Q5QJC3 457 50812 C296 P I V K G D M C Y A S F Q K Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5RGE5 639 71693 D411 R R K I T V S D L T T V A I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787553 599 67104 N395 S E E N S K G N G T N S D C Y
Poplar Tree Populus trichocarpa XP_002332533 360 41193 L199 V L N I K I W L W L E R L Q T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_174061 422 47744 P261 G I M P S G L P W V K R P F K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.3 81.5 N.A. 76.7 23.9 N.A. 56.3 48.1 N.A. 22.8 N.A. N.A. N.A. N.A. 31.2
Protein Similarity: 100 100 97.1 88.5 N.A. 84.8 39.5 N.A. 67.5 60.1 N.A. 37.8 N.A. N.A. N.A. N.A. 49.7
P-Site Identity: 100 100 86.6 20 N.A. 66.6 13.3 N.A. 6.6 0 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 40 N.A. 73.3 26.6 N.A. 46.6 20 N.A. 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 23.5 N.A. N.A. 25.9 N.A. N.A.
Protein Similarity: 39.2 N.A. N.A. 39.2 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 25 0 0 9 0 0 9 25 0 17 9 0 % A
% Cys: 0 0 0 0 0 0 0 17 9 0 0 0 0 9 0 % C
% Asp: 0 0 9 0 34 9 34 17 0 9 0 0 9 0 0 % D
% Glu: 9 9 9 9 0 0 9 0 0 0 9 9 0 34 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % F
% Gly: 9 0 9 0 9 9 17 0 17 9 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 17 0 17 0 9 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 17 9 9 17 0 0 34 42 9 34 42 9 42 % K
% Leu: 0 17 9 0 0 0 9 9 9 9 0 0 9 0 0 % L
% Met: 0 0 9 0 0 0 9 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 9 9 0 0 0 9 0 0 9 0 0 0 9 % N
% Pro: 17 0 0 9 0 9 0 17 0 0 0 0 9 0 9 % P
% Gln: 34 0 25 17 0 9 0 0 9 0 0 17 9 9 0 % Q
% Arg: 9 9 0 0 0 34 0 0 0 0 0 17 0 0 9 % R
% Ser: 9 34 0 0 42 0 9 34 0 0 25 9 9 0 0 % S
% Thr: 9 0 0 0 9 0 0 0 0 17 17 0 0 0 9 % T
% Val: 9 9 9 9 0 9 0 0 0 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 17 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _