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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1B All Species: 10.91
Human Site: S390 Identified Species: 21.82
UniProt: Q9H816 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H816 NP_073747.1 532 60002 S390 A D L E K Q P S H H P L R I K
Chimpanzee Pan troglodytes XP_524804 532 59965 S390 A D L E K Q P S H H P L R I K
Rhesus Macaque Macaca mulatta XP_001110949 532 60020 S390 A Y L E K Q P S H H P L R T K
Dog Lupus familis XP_848274 530 59628 P389 G E L E K Q K P S F L D L S S
Cat Felis silvestris
Mouse Mus musculus Q8C7W7 541 61051 P391 G H L E R L C P H P L Q A R K
Rat Rattus norvegicus Q5XIX3 698 78171 S453 N F V D C D E S N S D S E G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506464 563 63126 A393 P G D S P E Q A R L P A S P T
Chicken Gallus gallus Q5QJC3 457 50812 I316 Q A L P G L G I P K P L Q V S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5RGE5 639 71693 N431 A N A D S H D N D Q T Y S L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787553 599 67104 D415 T E L D E E A D K N E E D V A
Poplar Tree Populus trichocarpa XP_002332533 360 41193 K219 F H D T F T T K N S L T R V R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_174061 422 47744 S281 S G S F L T A S M K N E T V S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.3 81.5 N.A. 76.7 23.9 N.A. 56.3 48.1 N.A. 22.8 N.A. N.A. N.A. N.A. 31.2
Protein Similarity: 100 100 97.1 88.5 N.A. 84.8 39.5 N.A. 67.5 60.1 N.A. 37.8 N.A. N.A. N.A. N.A. 49.7
P-Site Identity: 100 100 86.6 26.6 N.A. 26.6 6.6 N.A. 6.6 20 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 86.6 33.3 N.A. 33.3 33.3 N.A. 20 33.3 N.A. 33.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: 23.5 N.A. N.A. 25.9 N.A. N.A.
Protein Similarity: 39.2 N.A. N.A. 39.2 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 9 9 0 0 0 17 9 0 0 0 9 9 0 9 % A
% Cys: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 17 25 0 9 9 9 9 0 9 9 9 0 0 % D
% Glu: 0 17 0 42 9 17 9 0 0 0 9 17 9 0 9 % E
% Phe: 9 9 0 9 9 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 17 17 0 0 9 0 9 0 0 0 0 0 0 9 0 % G
% His: 0 17 0 0 0 9 0 0 34 25 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 17 9 % I
% Lys: 0 0 0 0 34 0 9 9 9 17 0 0 0 0 34 % K
% Leu: 0 0 59 0 9 17 0 0 0 9 25 34 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 9 9 0 0 0 0 0 9 17 9 9 0 0 0 0 % N
% Pro: 9 0 0 9 9 0 25 17 9 9 42 0 0 9 0 % P
% Gln: 9 0 0 0 0 34 9 0 0 9 0 9 9 0 0 % Q
% Arg: 0 0 0 0 9 0 0 0 9 0 0 0 34 9 9 % R
% Ser: 9 0 9 9 9 0 0 42 9 17 0 9 17 9 25 % S
% Thr: 9 0 0 9 0 17 9 0 0 0 9 9 9 9 9 % T
% Val: 0 0 9 0 0 0 0 0 0 0 0 0 0 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _