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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1B All Species: 12.42
Human Site: S444 Identified Species: 24.85
UniProt: Q9H816 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H816 NP_073747.1 532 60002 S444 S T D E E F I S Q K T R E E I
Chimpanzee Pan troglodytes XP_524804 532 59965 S444 S T D E E F I S Q K T R E E I
Rhesus Macaque Macaca mulatta XP_001110949 532 60020 S444 S T D E E F L S L K T R E E I
Dog Lupus familis XP_848274 530 59628 V443 E T G E D M G V G P H L V P K
Cat Felis silvestris
Mouse Mus musculus Q8C7W7 541 61051 E445 I D E F L F P E T R E K I G L
Rat Rattus norvegicus Q5XIX3 698 78171 N507 I T D E C L E N L P S S I E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506464 563 63126 S447 S L A F P L K S P T L D R G D
Chicken Gallus gallus Q5QJC3 457 50812 T370 S D G L G G V T A P Q Q N S H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5RGE5 639 71693 K485 S T E K P C S K H T H S D S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787553 599 67104 T469 E P D L E K D T Q D N E P K V
Poplar Tree Populus trichocarpa XP_002332533 360 41193 L273 D N L F G S L L T S R Y K K R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_174061 422 47744 V335 P K S M K G I V V S S S S Y V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.3 81.5 N.A. 76.7 23.9 N.A. 56.3 48.1 N.A. 22.8 N.A. N.A. N.A. N.A. 31.2
Protein Similarity: 100 100 97.1 88.5 N.A. 84.8 39.5 N.A. 67.5 60.1 N.A. 37.8 N.A. N.A. N.A. N.A. 49.7
P-Site Identity: 100 100 86.6 13.3 N.A. 6.6 26.6 N.A. 13.3 6.6 N.A. 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 93.3 20 N.A. 33.3 40 N.A. 13.3 26.6 N.A. 33.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 23.5 N.A. N.A. 25.9 N.A. N.A.
Protein Similarity: 39.2 N.A. N.A. 39.2 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 17 42 0 9 0 9 0 0 9 0 9 9 0 9 % D
% Glu: 17 0 17 42 34 0 9 9 0 0 9 9 25 34 0 % E
% Phe: 0 0 0 25 0 34 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 0 17 17 9 0 9 0 0 0 0 17 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 17 0 0 0 9 % H
% Ile: 17 0 0 0 0 0 25 0 0 0 0 0 17 0 25 % I
% Lys: 0 9 0 9 9 9 9 9 0 25 0 9 9 17 9 % K
% Leu: 0 9 9 17 9 17 17 9 17 0 9 9 0 0 9 % L
% Met: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 9 0 0 9 0 9 0 0 % N
% Pro: 9 9 0 0 17 0 9 0 9 25 0 0 9 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 25 0 9 9 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 9 25 9 0 9 % R
% Ser: 50 0 9 0 0 9 9 34 0 17 17 25 9 17 9 % S
% Thr: 0 50 0 0 0 0 0 17 17 17 25 0 0 0 9 % T
% Val: 0 0 0 0 0 0 9 17 9 0 0 0 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _