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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL8
All Species:
9.7
Human Site:
S128
Identified Species:
21.33
UniProt:
Q9H825
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H825
NP_079046
291
33387
S128
P
E
E
K
A
R
E
S
S
W
D
H
V
K
T
Chimpanzee
Pan troglodytes
XP_001142282
407
46940
S128
P
E
E
K
A
R
E
S
S
W
D
H
V
K
T
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
L112
P
S
Q
N
Q
N
H
L
K
D
W
F
L
E
N
Dog
Lupus familis
XP_545519
414
47849
L141
T
E
Q
K
L
Q
E
L
S
W
D
H
A
K
T
Cat
Felis silvestris
Mouse
Mus musculus
A2AUU0
281
31651
N118
F
P
E
I
L
P
V
N
Q
N
T
K
E
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514374
410
46732
N131
E
E
K
K
I
P
R
N
H
V
N
T
N
G
A
Chicken
Gallus gallus
Q5ZHP8
370
42711
S164
A
P
Q
K
L
K
Q
S
Y
E
D
Y
P
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
T148
E
D
I
S
L
N
P
T
H
D
E
F
P
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
S128
L
A
P
L
A
A
D
S
A
V
L
Q
P
R
S
Honey Bee
Apis mellifera
XP_624474
332
39379
I145
P
S
K
N
G
N
K
I
L
E
I
G
C
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
D136
K
K
E
L
Y
E
A
D
A
D
R
Y
W
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.7
34
58.9
N.A.
70.4
N.A.
N.A.
47.5
32.7
N.A.
25.5
N.A.
21.5
27.4
N.A.
23.4
Protein Similarity:
100
71
46.7
64.2
N.A.
79.3
N.A.
N.A.
55.8
47.8
N.A.
40.2
N.A.
40
43.3
N.A.
37.2
P-Site Identity:
100
100
6.6
60
N.A.
13.3
N.A.
N.A.
13.3
20
N.A.
0
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
26.6
73.3
N.A.
20
N.A.
N.A.
33.3
53.3
N.A.
20
N.A.
40
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
28
10
10
0
19
0
0
0
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
10
0
0
0
0
10
10
0
28
37
0
0
0
0
% D
% Glu:
19
37
37
0
0
10
28
0
0
19
10
0
10
10
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
10
0
37
0
% G
% His:
0
0
0
0
0
0
10
0
19
0
0
28
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
10
10
19
46
0
10
10
0
10
0
0
10
0
37
0
% K
% Leu:
10
0
0
19
37
0
0
19
10
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
28
0
19
0
10
10
0
10
10
10
% N
% Pro:
37
19
10
0
0
19
10
0
0
0
0
0
28
0
0
% P
% Gln:
0
0
28
0
10
10
10
0
10
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
19
10
0
0
0
10
0
0
10
0
% R
% Ser:
0
19
0
10
0
0
0
37
28
0
0
0
0
0
19
% S
% Thr:
10
0
0
0
0
0
0
10
0
0
10
10
0
0
28
% T
% Val:
0
0
0
0
0
0
10
0
0
19
0
0
19
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
28
10
0
10
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
10
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _