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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL8
All Species:
14.24
Human Site:
S241
Identified Species:
31.33
UniProt:
Q9H825
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H825
NP_079046
291
33387
S241
G
A
V
E
L
V
K
S
H
S
S
Y
R
A
T
Chimpanzee
Pan troglodytes
XP_001142282
407
46940
S241
G
A
V
E
L
V
K
S
H
S
S
Y
R
A
T
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
T225
T
A
I
E
L
V
Q
T
N
P
E
Y
D
P
S
Dog
Lupus familis
XP_545519
414
47849
L254
G
A
V
E
L
V
K
L
H
S
S
Y
R
A
A
Cat
Felis silvestris
Mouse
Mus musculus
A2AUU0
281
31651
S231
E
A
V
E
L
V
K
S
H
E
S
Y
S
E
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514374
410
46732
S244
G
A
V
E
L
I
K
S
H
S
S
Y
S
P
A
Chicken
Gallus gallus
Q5ZHP8
370
42711
P277
K
L
S
R
L
L
K
P
G
G
M
I
L
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
P261
R
L
G
R
L
L
K
P
G
G
V
L
L
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
L241
L
R
P
G
G
L
L
L
F
R
D
Y
G
R
Y
Honey Bee
Apis mellifera
XP_624474
332
39379
D258
F
R
D
Y
G
R
Y
D
L
A
Q
L
R
F
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
Q249
V
A
V
D
I
V
R
Q
H
A
E
Y
N
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.7
34
58.9
N.A.
70.4
N.A.
N.A.
47.5
32.7
N.A.
25.5
N.A.
21.5
27.4
N.A.
23.4
Protein Similarity:
100
71
46.7
64.2
N.A.
79.3
N.A.
N.A.
55.8
47.8
N.A.
40.2
N.A.
40
43.3
N.A.
37.2
P-Site Identity:
100
100
33.3
86.6
N.A.
66.6
N.A.
N.A.
73.3
13.3
N.A.
13.3
N.A.
6.6
6.6
N.A.
33.3
P-Site Similarity:
100
100
66.6
86.6
N.A.
66.6
N.A.
N.A.
80
20
N.A.
20
N.A.
13.3
13.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
64
0
0
0
0
0
0
0
19
0
0
0
28
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
10
0
0
10
0
10
0
0
% D
% Glu:
10
0
0
55
0
0
0
0
0
10
19
0
0
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
37
0
10
10
19
0
0
0
19
19
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
55
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
10
0
0
0
0
0
64
0
0
0
0
0
0
0
10
% K
% Leu:
10
19
0
0
73
28
10
19
10
0
0
19
19
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
19
0
10
0
0
0
28
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% Q
% Arg:
10
19
0
19
0
10
10
0
0
10
0
0
37
10
19
% R
% Ser:
0
0
10
0
0
0
0
37
0
37
46
0
19
0
19
% S
% Thr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
19
% T
% Val:
10
0
55
0
0
55
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
73
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _