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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL8
All Species:
12.12
Human Site:
S243
Identified Species:
26.67
UniProt:
Q9H825
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H825
NP_079046
291
33387
S243
V
E
L
V
K
S
H
S
S
Y
R
A
T
Q
C
Chimpanzee
Pan troglodytes
XP_001142282
407
46940
S243
V
E
L
V
K
S
H
S
S
Y
R
A
T
Q
C
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
P227
I
E
L
V
Q
T
N
P
E
Y
D
P
S
R
C
Dog
Lupus familis
XP_545519
414
47849
S256
V
E
L
V
K
L
H
S
S
Y
R
A
A
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
A2AUU0
281
31651
E233
V
E
L
V
K
S
H
E
S
Y
S
E
A
Q
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514374
410
46732
S246
V
E
L
I
K
S
H
S
S
Y
S
P
A
Q
C
Chicken
Gallus gallus
Q5ZHP8
370
42711
G279
S
R
L
L
K
P
G
G
M
I
L
L
R
D
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
G263
G
R
L
L
K
P
G
G
V
L
L
L
R
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
R243
P
G
G
L
L
L
F
R
D
Y
G
R
Y
D
L
Honey Bee
Apis mellifera
XP_624474
332
39379
A260
D
Y
G
R
Y
D
L
A
Q
L
R
F
K
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
A251
V
D
I
V
R
Q
H
A
E
Y
N
P
S
R
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.7
34
58.9
N.A.
70.4
N.A.
N.A.
47.5
32.7
N.A.
25.5
N.A.
21.5
27.4
N.A.
23.4
Protein Similarity:
100
71
46.7
64.2
N.A.
79.3
N.A.
N.A.
55.8
47.8
N.A.
40.2
N.A.
40
43.3
N.A.
37.2
P-Site Identity:
100
100
33.3
86.6
N.A.
73.3
N.A.
N.A.
73.3
13.3
N.A.
13.3
N.A.
6.6
6.6
N.A.
33.3
P-Site Similarity:
100
100
73.3
86.6
N.A.
73.3
N.A.
N.A.
80
20
N.A.
20
N.A.
13.3
20
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
0
0
0
28
28
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% C
% Asp:
10
10
0
0
0
10
0
0
10
0
10
0
0
28
0
% D
% Glu:
0
55
0
0
0
0
0
10
19
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
19
0
0
0
19
19
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
55
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
64
0
0
0
0
0
0
0
10
10
0
% K
% Leu:
0
0
73
28
10
19
10
0
0
19
19
19
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
10
0
0
0
0
19
0
10
0
0
0
28
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
0
10
0
0
0
0
46
0
% Q
% Arg:
0
19
0
10
10
0
0
10
0
0
37
10
19
19
0
% R
% Ser:
10
0
0
0
0
37
0
37
46
0
19
0
19
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
19
0
0
% T
% Val:
55
0
0
55
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
0
0
73
0
0
10
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _