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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL8
All Species:
9.39
Human Site:
T148
Identified Species:
20.67
UniProt:
Q9H825
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H825
NP_079046
291
33387
T148
F
S
R
M
H
C
P
T
V
P
D
E
K
N
H
Chimpanzee
Pan troglodytes
XP_001142282
407
46940
T148
F
S
R
M
H
C
P
T
V
P
D
E
K
N
H
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
D132
P
E
C
R
N
N
E
D
G
P
S
L
I
M
E
Dog
Lupus familis
XP_545519
414
47849
T161
F
S
R
M
H
C
P
T
M
P
E
E
K
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
A2AUU0
281
31651
S138
D
Q
V
G
S
S
I
S
R
T
Q
G
T
E
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514374
410
46732
M151
V
P
P
P
A
I
P
M
E
E
R
N
S
C
K
Chicken
Gallus gallus
Q5ZHP8
370
42711
A184
I
L
E
V
G
C
G
A
G
N
T
V
F
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
V168
I
L
E
V
G
C
G
V
G
N
T
V
F
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
L148
C
G
V
G
N
T
I
L
P
L
L
Q
Y
S
S
Honey Bee
Apis mellifera
XP_624474
332
39379
D165
P
I
L
L
Y
N
T
D
A
N
L
F
V
Y
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
R156
Q
H
K
F
F
K
D
R
H
W
L
F
T
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.7
34
58.9
N.A.
70.4
N.A.
N.A.
47.5
32.7
N.A.
25.5
N.A.
21.5
27.4
N.A.
23.4
Protein Similarity:
100
71
46.7
64.2
N.A.
79.3
N.A.
N.A.
55.8
47.8
N.A.
40.2
N.A.
40
43.3
N.A.
37.2
P-Site Identity:
100
100
6.6
80
N.A.
0
N.A.
N.A.
6.6
6.6
N.A.
6.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
6.6
N.A.
N.A.
6.6
13.3
N.A.
13.3
N.A.
20
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% A
% Cys:
10
0
10
0
0
46
0
0
0
0
0
0
0
10
10
% C
% Asp:
10
0
0
0
0
0
10
19
0
0
19
0
0
0
0
% D
% Glu:
0
10
19
0
0
0
10
0
10
10
10
28
0
19
10
% E
% Phe:
28
0
0
10
10
0
0
0
0
0
0
19
19
0
10
% F
% Gly:
0
10
0
19
19
0
19
0
28
0
0
10
0
0
0
% G
% His:
0
10
0
0
28
0
0
0
10
0
0
0
0
0
19
% H
% Ile:
19
10
0
0
0
10
19
0
0
0
0
0
10
0
19
% I
% Lys:
0
0
10
0
0
10
0
0
0
0
0
0
28
0
10
% K
% Leu:
0
19
10
10
0
0
0
10
0
10
28
10
0
0
0
% L
% Met:
0
0
0
28
0
0
0
10
10
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
19
19
0
0
0
28
0
10
0
28
0
% N
% Pro:
19
10
10
10
0
0
37
0
10
37
0
0
0
19
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% Q
% Arg:
0
0
28
10
0
0
0
10
10
0
10
0
0
0
0
% R
% Ser:
0
28
0
0
10
10
0
10
0
0
10
0
10
10
10
% S
% Thr:
0
0
0
0
0
10
10
28
0
10
19
0
19
0
10
% T
% Val:
10
0
19
19
0
0
0
10
19
0
0
19
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _