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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL8
All Species:
13.03
Human Site:
T217
Identified Species:
28.67
UniProt:
Q9H825
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H825
NP_079046
291
33387
T217
S
V
F
P
I
L
N
T
L
E
N
S
P
E
S
Chimpanzee
Pan troglodytes
XP_001142282
407
46940
T217
S
V
F
P
I
L
N
T
L
Q
N
S
P
E
S
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
Q201
N
T
V
F
P
I
L
Q
T
N
N
D
P
G
L
Dog
Lupus familis
XP_545519
414
47849
T230
S
V
F
P
I
L
N
T
L
Q
D
A
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
A2AUU0
281
31651
T207
S
V
F
P
I
L
N
T
L
Q
N
I
P
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514374
410
46732
I220
S
V
F
P
I
L
N
I
L
N
K
T
P
G
T
Chicken
Gallus gallus
Q5ZHP8
370
42711
I253
S
L
D
I
V
I
L
I
F
V
L
S
A
I
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
I237
S
L
D
V
I
V
L
I
F
V
L
S
A
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
A217
V
M
I
F
V
L
S
A
I
E
P
K
K
M
Q
Honey Bee
Apis mellifera
XP_624474
332
39379
H234
I
N
P
E
K
M
K
H
I
I
E
Q
I
H
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
Q225
N
T
I
F
P
I
L
Q
T
N
A
D
P
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.7
34
58.9
N.A.
70.4
N.A.
N.A.
47.5
32.7
N.A.
25.5
N.A.
21.5
27.4
N.A.
23.4
Protein Similarity:
100
71
46.7
64.2
N.A.
79.3
N.A.
N.A.
55.8
47.8
N.A.
40.2
N.A.
40
43.3
N.A.
37.2
P-Site Identity:
100
93.3
13.3
80
N.A.
80
N.A.
N.A.
60
13.3
N.A.
20
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
86.6
N.A.
N.A.
73.3
33.3
N.A.
33.3
N.A.
40
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
10
10
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
0
0
0
0
0
10
19
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
19
10
0
0
28
0
% E
% Phe:
0
0
46
28
0
0
0
0
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
37
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% H
% Ile:
10
0
19
10
55
28
0
28
19
10
0
10
10
10
0
% I
% Lys:
0
0
0
0
10
0
10
0
0
0
10
10
10
0
10
% K
% Leu:
0
19
0
0
0
55
37
0
46
0
19
0
0
10
28
% L
% Met:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% M
% Asn:
19
10
0
0
0
0
46
0
0
28
37
0
0
0
0
% N
% Pro:
0
0
10
46
19
0
0
0
0
0
10
0
64
0
0
% P
% Gln:
0
0
0
0
0
0
0
19
0
28
0
10
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
64
0
0
0
0
0
10
0
0
0
0
37
0
0
37
% S
% Thr:
0
19
0
0
0
0
0
37
19
0
0
10
0
0
10
% T
% Val:
10
46
10
10
19
10
0
0
0
19
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _