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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL8
All Species:
19.39
Human Site:
Y88
Identified Species:
42.67
UniProt:
Q9H825
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H825
NP_079046
291
33387
Y88
Y
E
R
E
A
S
K
Y
W
D
T
F
Y
K
I
Chimpanzee
Pan troglodytes
XP_001142282
407
46940
Y88
Y
E
R
E
A
S
K
Y
W
D
T
F
Y
K
I
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
F89
Y
K
I
H
E
N
G
F
F
K
D
R
H
W
L
Dog
Lupus familis
XP_545519
414
47849
Y101
F
E
N
E
A
S
K
Y
W
D
T
F
Y
K
I
Cat
Felis silvestris
Mouse
Mus musculus
A2AUU0
281
31651
Y88
F
E
S
D
A
N
K
Y
W
D
I
F
Y
Q
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514374
410
46732
Y88
Y
E
N
E
A
S
K
Y
W
N
D
F
Y
K
T
Chicken
Gallus gallus
Q5ZHP8
370
42711
A138
H
C
T
L
E
N
R
A
E
N
Q
L
N
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
Y92
F
D
N
R
A
N
E
Y
W
N
D
F
Y
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
F95
F
Q
T
D
A
P
K
F
W
D
S
F
Y
G
I
Honey Bee
Apis mellifera
XP_624474
332
39379
F118
N
I
K
Q
P
L
R
F
K
N
E
N
I
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
A104
H
N
A
W
D
N
V
A
W
D
P
E
Q
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.7
34
58.9
N.A.
70.4
N.A.
N.A.
47.5
32.7
N.A.
25.5
N.A.
21.5
27.4
N.A.
23.4
Protein Similarity:
100
71
46.7
64.2
N.A.
79.3
N.A.
N.A.
55.8
47.8
N.A.
40.2
N.A.
40
43.3
N.A.
37.2
P-Site Identity:
100
100
6.6
86.6
N.A.
53.3
N.A.
N.A.
73.3
0
N.A.
40
N.A.
46.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
46.6
93.3
N.A.
80
N.A.
N.A.
80
33.3
N.A.
73.3
N.A.
80
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
64
0
0
19
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
19
10
0
0
0
0
55
28
0
0
0
0
% D
% Glu:
0
46
0
37
19
0
10
0
10
0
10
10
0
0
10
% E
% Phe:
37
0
0
0
0
0
0
28
10
0
0
64
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% G
% His:
19
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
10
0
10
0
46
% I
% Lys:
0
10
10
0
0
0
55
0
10
10
0
0
0
46
10
% K
% Leu:
0
0
0
10
0
10
0
0
0
0
0
10
0
19
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
28
0
0
46
0
0
0
37
0
10
10
0
0
% N
% Pro:
0
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
10
0
10
0
0
0
0
0
0
10
0
10
10
0
% Q
% Arg:
0
0
19
10
0
0
19
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
0
0
37
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
19
0
0
0
0
0
0
0
28
0
0
10
19
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
73
0
0
0
0
10
0
% W
% Tyr:
37
0
0
0
0
0
0
55
0
0
0
0
64
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _