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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC12 All Species: 23.64
Human Site: S191 Identified Species: 52
UniProt: Q9H892 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H892 NP_060338.3 705 78738 S191 N L A L K N Y S V S R E C Y K
Chimpanzee Pan troglodytes XP_508759 732 81550 S191 N L A L K N Y S V S R E C Y K
Rhesus Macaque Macaca mulatta XP_001084630 705 78442 S191 N L A L K N Y S V S R E C Y K
Dog Lupus familis XP_536570 689 77080 N175 H L A L K N Y N M S R E C Y Q
Cat Felis silvestris
Mouse Mus musculus Q8BW49 704 78735 S190 H V A L K N Y S K A K E C Y Q
Rat Rattus norvegicus NP_001004246 704 78845 S190 H L A L K N Y S K S K E C Y Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521579 596 64809 A134 L A S R K S T A V A T K T L L
Chicken Gallus gallus
Frog Xenopus laevis Q6NU95 660 75087 T156 D E A I E C Y T R G M D A D P
Zebra Danio Brachydanio rerio XP_692245 1008 111628 T198 H L A L K D F T Q S R I C Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794332 573 63704 K111 K A L L G Q L K Y D E A E E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12118 346 37200
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 95.1 76.3 N.A. 75 77 N.A. 49.2 N.A. 20.7 26.8 N.A. N.A. N.A. N.A. 27.8
Protein Similarity: 100 94.4 97.8 87.5 N.A. 88.6 89.6 N.A. 62.7 N.A. 41.4 44.8 N.A. N.A. N.A. N.A. 46.6
P-Site Identity: 100 100 100 73.3 N.A. 60 73.3 N.A. 13.3 N.A. 13.3 53.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 46.6 N.A. 46.6 86.6 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 31.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 73 0 0 0 0 10 0 19 0 10 10 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 64 0 0 % C
% Asp: 10 0 0 0 0 10 0 0 0 10 0 10 0 10 0 % D
% Glu: 0 10 0 0 10 0 0 0 0 0 10 55 10 10 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % G
% His: 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 10 0 0 0 73 0 0 10 19 0 19 10 0 0 28 % K
% Leu: 10 55 10 73 0 0 10 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % M
% Asn: 28 0 0 0 0 55 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 28 % Q
% Arg: 0 0 0 10 0 0 0 0 10 0 46 0 0 0 10 % R
% Ser: 0 0 10 0 0 10 0 46 0 55 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 10 19 0 0 10 0 10 0 0 % T
% Val: 0 10 0 0 0 0 0 0 37 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 64 0 10 0 0 0 0 64 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _